Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT57_RS11485 Genome accession   NZ_CP108055
Coordinates   2515823..2516464 (-) Length   213 a.a.
NCBI ID   WP_328746045.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00285     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2510823..2521464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT57_RS11450 (OHT57_11470) - 2510853..2511359 (+) 507 WP_328746038.1 HNH endonuclease -
  OHT57_RS11455 (OHT57_11475) - 2511493..2512431 (-) 939 WP_328746039.1 SPFH domain-containing protein -
  OHT57_RS11460 (OHT57_11480) - 2512563..2512994 (-) 432 WP_328746040.1 NfeD family protein -
  OHT57_RS11465 (OHT57_11485) - 2513089..2513886 (-) 798 WP_328746041.1 ABC transporter ATP-binding protein -
  OHT57_RS11470 (OHT57_11490) - 2514026..2514814 (+) 789 WP_328746042.1 hypothetical protein -
  OHT57_RS11475 (OHT57_11495) - 2514988..2515227 (-) 240 WP_328746043.1 chaplin family protein -
  OHT57_RS11480 (OHT57_11500) chpE 2515422..2515667 (-) 246 WP_328746044.1 chaplin ChpE -
  OHT57_RS11485 (OHT57_11505) vraR 2515823..2516464 (-) 642 WP_328746045.1 response regulator transcription factor Regulator
  OHT57_RS11490 (OHT57_11510) - 2516457..2517602 (-) 1146 WP_328746046.1 GAF domain-containing sensor histidine kinase -
  OHT57_RS11495 (OHT57_11515) - 2517951..2518649 (+) 699 WP_328746047.1 SDR family NAD(P)-dependent oxidoreductase -
  OHT57_RS11500 (OHT57_11520) - 2518646..2519752 (+) 1107 WP_328746048.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHT57_RS11505 (OHT57_11525) - 2520057..2520797 (+) 741 WP_328746049.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23085.48 Da        Isoelectric Point: 5.3711

>NTDB_id=652258 OHT57_RS11485 WP_328746045.1 2515823..2516464(-) (vraR) [Streptomyces sp. NBC_00285]
MADAIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELKPDIVLMDVKMPGMDGIDALRKLRELNNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGVLLSQEENNSGQGRGGSLTEREREVL
MLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGMAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=652258 OHT57_RS11485 WP_328746045.1 2515823..2516464(-) (vraR) [Streptomyces sp. NBC_00285]
GTGGCTGACGCGATCAGGGTCCTGCTCGTCGACGACCACCAGGTCGTCCGCCGCGGTCTGCGCACCTTCCTCGAGGTGCA
GGACGACATAGAGGTCGTGGGGGAGGCGGCCGACGGTGCCGAAGGTGTCGCGCGCGCGGAGGAACTGAAGCCCGACATCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCATCGACGCCCTGCGCAAGCTCCGCGAACTGAACAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAACAGCGCACCGTGGTCCCGGCCCTGCGCGCGGGCGCCGCGGGATACGTATATAA
GGACGTCGACCCCGACGCCCTGGCCGGTGCCATCCGCTCCGTGCATGCCGGCCACATCCTGCTCCAACCCGAGGTCGCGG
GCGTCCTGTTGTCCCAGGAGGAGAACAACTCCGGCCAGGGCCGAGGCGGTTCGCTCACCGAACGGGAGCGCGAGGTGCTC
ATGCTGATCGCCGACGGCCGCTCCAACCGGGAGATCGCCCGCGCGCTGGTGCTCTCCGAGAAGACCGTCAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGCACACAGGCGGCACTGTGGGCGGTTCGCCACGGTATGGCCGGTT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.498

99.061

0.451
  degU Bacillus subtilis subsp. subtilis str. 168

37.557

100

0.39