Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT57_RS08280 Genome accession   NZ_CP108055
Coordinates   1823822..1824484 (+) Length   220 a.a.
NCBI ID   WP_328745414.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00285     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1818822..1829484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT57_RS08260 (OHT57_08285) mug 1820131..1820676 (+) 546 WP_328745410.1 G/U mismatch-specific DNA glycosylase -
  OHT57_RS08265 (OHT57_08290) - 1820858..1821607 (-) 750 WP_328745411.1 ABC transporter permease -
  OHT57_RS08270 (OHT57_08295) - 1821609..1822529 (-) 921 WP_328745412.1 ABC transporter ATP-binding protein -
  OHT57_RS08275 (OHT57_08300) - 1822638..1823807 (+) 1170 WP_328745413.1 histidine kinase -
  OHT57_RS08280 (OHT57_08305) vraR 1823822..1824484 (+) 663 WP_328745414.1 response regulator transcription factor Regulator
  OHT57_RS08285 (OHT57_08310) - 1824721..1825878 (+) 1158 WP_328753148.1 ROK family transcriptional regulator -
  OHT57_RS08290 (OHT57_08315) - 1825922..1826683 (-) 762 WP_328745415.1 GntR family transcriptional regulator -
  OHT57_RS08295 (OHT57_08320) - 1826877..1827761 (-) 885 WP_328745416.1 RNA polymerase sigma-70 factor -
  OHT57_RS08300 (OHT57_08325) - 1827917..1828747 (+) 831 WP_328745418.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23623.24 Da        Isoelectric Point: 5.0141

>NTDB_id=652252 OHT57_RS08280 WP_328745414.1 1823822..1824484(+) (vraR) [Streptomyces sp. NBC_00285]
MPITVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRTIEEPPKI
VVITTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLPFPASVRRLAARYGDDGGNRAARATMERAQLTER
EAEVLRLMARGLSNGEIAGRLIVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=652252 OHT57_RS08280 WP_328745414.1 1823822..1824484(+) (vraR) [Streptomyces sp. NBC_00285]
ATGCCGATCACCGTCCTCCTCGTCGACGACGAACCTCTCGTACGCGCCGGGCTGCGGGCGGTGCTGGAGGCGCAGCCCGA
CATCGAGGTCGTCGGCGAGGCGGCCGACGGGGCGGCGGTGATCCCCCTCGTGCGGCAACTGCGGCCCGACGTGGTCGCCA
TGGACGTACGGATGCCTCTGCTGGACGGCATCGAGGCCACCCGCGCGGTGCTGCGCACCATCGAGGAGCCGCCGAAGATC
GTCGTCATCACGACGTTCGAGAACGACGAGTACGTGTACGAGGCCCTGCGGGCGGGCGCCGACGGGTTTCTGTTGAAACG
GGCGCGGCCGGCCGAGATCGTGCACGCGGTGCGGTTGGTCGCCGAGGGCGAGTCGCTGCCGTTCCCCGCTTCGGTGCGCC
GGCTCGCCGCCCGGTACGGCGACGACGGCGGCAACCGGGCGGCCCGCGCGACGATGGAGCGGGCCCAGCTGACCGAGCGG
GAGGCCGAGGTGCTGCGGCTGATGGCCCGCGGCCTGTCGAACGGGGAGATCGCCGGGCGGCTGATCGTCGGCACGGAGAC
CGTCAAGTCGCATGTGAGCGCGGTCCTGGCGAAGCTGGGGGCGCGCGACCGTACCCAGGCCGTGATCGCGGCGTACGAGT
CGGGCTTCGTCGCACCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.475

98.636

0.409
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.368