Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT57_RS05795 Genome accession   NZ_CP108055
Coordinates   1231537..1232202 (-) Length   221 a.a.
NCBI ID   WP_328744955.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00285     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1226537..1237202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT57_RS05765 (OHT57_05790) - 1226799..1227494 (-) 696 WP_328744949.1 type 1 glutamine amidotransferase domain-containing protein -
  OHT57_RS05770 (OHT57_05795) - 1227545..1228489 (+) 945 WP_328744950.1 LysR family transcriptional regulator -
  OHT57_RS05775 (OHT57_05800) - 1228517..1229254 (+) 738 WP_328744951.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHT57_RS05780 (OHT57_05805) - 1229251..1229631 (-) 381 WP_328744952.1 MarR family transcriptional regulator -
  OHT57_RS05785 (OHT57_05810) - 1229718..1231208 (+) 1491 WP_328744953.1 MFS transporter -
  OHT57_RS05790 (OHT57_05815) - 1231289..1231576 (+) 288 WP_328744954.1 DUF6332 family protein -
  OHT57_RS05795 (OHT57_05820) vraR 1231537..1232202 (-) 666 WP_328744955.1 response regulator transcription factor Regulator
  OHT57_RS05800 (OHT57_05825) - 1232199..1233437 (-) 1239 WP_328744956.1 sensor histidine kinase -
  OHT57_RS05805 (OHT57_05830) - 1233520..1234215 (-) 696 WP_328744957.1 TetR/AcrR family transcriptional regulator -
  OHT57_RS05810 (OHT57_05835) - 1234350..1234799 (+) 450 WP_328744958.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHT57_RS05815 (OHT57_05840) - 1234804..1236045 (-) 1242 WP_328753127.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23869.66 Da        Isoelectric Point: 4.7161

>NTDB_id=652248 OHT57_RS05795 WP_328744955.1 1231537..1232202(-) (vraR) [Streptomyces sp. NBC_00285]
MIRVLLADDQSLVRAGFRALLDAQPDIEVAGEAADGEEAVGKVRELRPDIVLMDIRMPLLDGLAATRRITGDAALCEVRV
VMLTTFELDEYVFEAIRAGASGFLVKDTEPEELLRAVRAVVDGDALLSPGVTRRLIAEFAARSKEPAAEGALAELTERER
EVMALVGIGLSNAEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=652248 OHT57_RS05795 WP_328744955.1 1231537..1232202(-) (vraR) [Streptomyces sp. NBC_00285]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTCGTGCGTGCCGGCTTCCGCGCGCTGCTGGACGCGCAGCCGGACAT
CGAGGTGGCCGGGGAGGCCGCCGATGGTGAGGAGGCGGTCGGGAAGGTGCGCGAACTGCGGCCGGACATCGTGCTGATGG
ACATCCGCATGCCCCTGCTCGACGGCCTCGCCGCGACCCGGCGCATCACCGGGGACGCCGCTCTGTGCGAAGTTCGGGTG
GTCATGCTCACCACCTTCGAACTGGACGAGTACGTCTTCGAGGCGATCCGTGCCGGCGCCTCCGGTTTCCTGGTCAAGGA
CACCGAGCCGGAGGAACTCCTGCGCGCCGTACGGGCCGTGGTCGACGGTGACGCGCTTCTCTCGCCGGGTGTGACCCGCC
GTCTCATCGCCGAGTTCGCGGCCCGCTCCAAGGAGCCCGCGGCCGAGGGTGCCCTCGCCGAACTCACCGAGCGGGAACGG
GAGGTGATGGCCCTGGTCGGCATCGGCCTGTCCAACGCGGAGATCGCCCGCCGCCTGGTCGTCAGCCCCCTCACCGCCAA
GACCCACGTCAGCCGCACGATGGTGAAGCTGGGCGCCCGGGATCGCGCCCAACTCGTCGTGCTGGCCTACGAGTCGGGGT
TGGTGCGGCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.889

97.738

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

35.556

100

0.362