Detailed information NTG0652105

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHT76_RS24450
• Genome accession: NZ_CP108053
• Coordinates: 5365307..5366431 (-)
• Length: 374 a.a.
• NCBI ID: WP_328872999.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00287
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5360307..5371431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHT76_RS24420 (OHT76_24440)	cseB	5360651..5361355 (-)	705	WP_328872995.1	two-component system response regulator CseB	-
OHT76_RS24425 (OHT76_24445)	-	5361439..5362050 (-)	612	WP_328872996.1	hypothetical protein	-
OHT76_RS24430 (OHT76_24450)	-	5362101..5362640 (-)	540	WP_186283894.1	SigE family RNA polymerase sigma factor	-
OHT76_RS24435 (OHT76_24455)	-	5362862..5363779 (-)	918	WP_328872997.1	A/G-specific adenine glycosylase	-
OHT76_RS24440 (OHT76_24460)	-	5364004..5364090 (+)	87	Protein_4819	histidine kinase	-
OHT76_RS24445 (OHT76_24465)	-	5364422..5365249 (+)	828	WP_328872998.1	hypothetical protein	-
OHT76_RS24450 (OHT76_24470)	disA	5365307..5366431 (-)	1125	WP_328872999.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHT76_RS24455 (OHT76_24475)	radA/sms	5366513..5367922 (-)	1410	WP_328873000.1	DNA repair protein RadA	Machinery gene
OHT76_RS24460 (OHT76_24480)	-	5368140..5369885 (+)	1746	WP_328873001.1	hypothetical protein	-
OHT76_RS24465 (OHT76_24485)	-	5369898..5370746 (-)	849	WP_328873002.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40056.80 Da
• Isoelectric Point: 4.9235

>NTDB_id=652105 OHT76_RS24450 WP_328872999.1 5365307..5366431(-) (disA) [Streptomyces sp. NBC_00287]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVEEALYELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=652105 OHT76_RS24450 WP_328872999.1 5365307..5366431(-) (disA) [Streptomyces sp. NBC_00287]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCACCCGGCACGGCCCTGCGCGACGGCCTTGAGCGGATCCTCCGCGGCAACACCGGAGGGCTTATCGTGC
TGGGCTCCGACAAGACCGTCGAGGCCATGTGCACGGGTGGATTCGTGCTGGATGTCGAGTTCACGGCGACCCGGCTGCGG
GAGCTGTGCAAGCTGGACGGCGGCATCGTGCTCTCCTCCGACCTGTCGAAGATCCTTCGTGCCGGTGTGCAGCTGGTGCC
GGATCCGACGATCCCCACGGAAGAGACGGGCACACGGCACCGTACGGCGGACCGGGTCAGCAAGCAGGTCGGGTTCCCCG
TCGTCTCCGTCTCCCAGTCCATGCGGCTGATCGCCCTGTACGTCGACGGGCAGCGGCGGGTGCTGGAGGACTCCGCGGCG
ATTCTGTCCCGGGCGAATCAGGCGCTGGCGACCCTTGAGCGGTACAAGCTGCGCCTTGACGAGGTCGCGGGAACGTTGTC
AGCGCTGGAGATCGAGGACCTTGTGACGGTCCGGGATGTCTCGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CTACCGAAATCGCCGAGTATGTGGTGGAGCTGGGTACCGACGGGCGGCTTCTCGCGCTTCAGCTGGACGAGTTGATCGCG
GGTGTGGAGCCCGAGCGGGAGCTCGTGGTCCGGGACTATGTGCCCGAGCCGACGGCCAAGCGGTCCCGTACGGTCGAGGA
GGCGCTGTACGAGCTGGACGCGCTGAGCCATGCGGAGCTGTTGGAACTGCCCACGGTGGCTCGGGCGTTGGGGTACACAG
GGTCGCCCGAAGCGCTGGACTCCGCGGTGTCGCCGCGTGGGTTCCGGCTGCTGGCGAAGGTGCCTCGGCTGCCCGGGGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGATCTGCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGGAGCGTGCGCGAGGGGCTGTCGCGGTTGGCGGAGTCTTCGATTCTCGAGAGGTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441