Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT76_RS23340 Genome accession   NZ_CP108053
Coordinates   5107285..5107950 (-) Length   221 a.a.
NCBI ID   WP_328872804.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00287     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5102285..5112950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT76_RS23310 (OHT76_23330) - 5103609..5104049 (+) 441 WP_328872798.1 hypothetical protein -
  OHT76_RS23315 (OHT76_23335) - 5104111..5104782 (+) 672 WP_328872799.1 class I SAM-dependent methyltransferase -
  OHT76_RS23320 (OHT76_23340) - 5104757..5104942 (-) 186 WP_328872800.1 DUF397 domain-containing protein -
  OHT76_RS23325 (OHT76_23345) - 5104942..5105793 (-) 852 WP_328872801.1 helix-turn-helix transcriptional regulator -
  OHT76_RS23330 (OHT76_23350) - 5106014..5106427 (+) 414 WP_328872802.1 ATP-binding protein -
  OHT76_RS23335 (OHT76_23355) - 5106466..5107284 (+) 819 WP_328872803.1 hypothetical protein -
  OHT76_RS23340 (OHT76_23360) vraR 5107285..5107950 (-) 666 WP_328872804.1 response regulator transcription factor Regulator
  OHT76_RS23345 (OHT76_23365) - 5107947..5109266 (-) 1320 WP_328872805.1 histidine kinase -
  OHT76_RS23350 (OHT76_23370) - 5109352..5110206 (-) 855 WP_328872806.1 alpha/beta hydrolase -
  OHT76_RS23355 (OHT76_23375) - 5110419..5111624 (+) 1206 WP_328872807.1 cytochrome P450 -
  OHT76_RS23360 (OHT76_23380) - 5111729..5112322 (+) 594 WP_328872808.1 Uma2 family endonuclease -
  OHT76_RS23365 (OHT76_23385) - 5112333..5112557 (-) 225 WP_328872809.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23910.65 Da        Isoelectric Point: 4.6550

>NTDB_id=652098 OHT76_RS23340 WP_328872804.1 5107285..5107950(-) (vraR) [Streptomyces sp. NBC_00287]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVAKVRELAPDVVLMDIRMPELNGIEATREIVAADGTAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPSVTRRLITEFSKLSETPRVMVGTQSAYGDLTE
RETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=652098 OHT76_RS23340 WP_328872804.1 5107285..5107950(-) (vraR) [Streptomyces sp. NBC_00287]
ATGACGATCCGCGTACTGATCGCGGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTCAACGCGATGCCGGA
CATCGAGGTCGTCGGCGAGGCGGTGAACGGCCGGGAGGCCGTGGCGAAGGTCCGCGAACTCGCCCCGGACGTCGTCCTGA
TGGACATCCGCATGCCCGAACTGAACGGCATCGAGGCGACCAGGGAGATCGTGGCGGCGGACGGTACGGCGAAGGTGCTG
GTGCTGACGACGTTCGACCTGGACGAGTACGTGTACCAGGCGCTGCGGGCGGGAGCCTCGGGCTTCCTGCTGAAGGACGC
GTCGGCACGCCAACTGGCGGACGGGGTACGGGTGGTGGCCTCCGGAGAGGCGTTGTTGGCGCCCTCGGTTACCCGGCGCC
TGATCACGGAGTTCTCCAAACTCTCGGAGACCCCGCGCGTGATGGTGGGCACGCAGTCGGCATACGGCGACCTCACCGAA
CGCGAGACGGAGGTCCTGGTCCTGATCGCCCAGGGCCTGTCCAACGCGGAGATCGCCGAGCGCCTGGTCGTGGCCGAGTC
GACGATCAAGACCCATGTGAGCCGGATCCTGGTGAAACTGGGCCTCAGGGACCGCACCCAGGCGGCGGTGTTCGCGTACG
AGGCGCGGCTGGTGACGCCCGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.413

98.643

0.448
  degU Bacillus subtilis subsp. subtilis str. 168

41.935

98.19

0.412