Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT76_RS09840 Genome accession   NZ_CP108053
Coordinates   2160536..2161177 (-) Length   213 a.a.
NCBI ID   WP_328870379.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00287     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2155536..2166177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT76_RS09810 (OHT76_09840) - 2156152..2156658 (+) 507 WP_328870374.1 HNH endonuclease -
  OHT76_RS09815 (OHT76_09845) - 2156725..2157672 (-) 948 WP_328870375.1 SPFH domain-containing protein -
  OHT76_RS09820 (OHT76_09850) - 2157828..2158259 (-) 432 WP_328870376.1 NfeD family protein -
  OHT76_RS09825 (OHT76_09855) - 2158313..2159104 (-) 792 WP_328870377.1 ABC transporter ATP-binding protein -
  OHT76_RS09830 (OHT76_09860) - 2159243..2160031 (+) 789 WP_328870378.1 hypothetical protein -
  OHT76_RS09835 (OHT76_09865) chpE 2160132..2160380 (-) 249 WP_315888526.1 chaplin ChpE -
  OHT76_RS09840 (OHT76_09870) vraR 2160536..2161177 (-) 642 WP_328870379.1 response regulator transcription factor Regulator
  OHT76_RS09845 (OHT76_09875) - 2161170..2162315 (-) 1146 WP_328870380.1 GAF domain-containing sensor histidine kinase -
  OHT76_RS09850 (OHT76_09880) - 2162549..2163247 (+) 699 WP_328870381.1 SDR family NAD(P)-dependent oxidoreductase -
  OHT76_RS09855 (OHT76_09885) - 2163244..2164329 (+) 1086 WP_328870382.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHT76_RS09860 (OHT76_09890) - 2164629..2165375 (+) 747 WP_328870383.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22896.15 Da        Isoelectric Point: 5.1490

>NTDB_id=652070 OHT76_RS09840 WP_328870379.1 2160536..2161177(-) (vraR) [Streptomyces sp. NBC_00287]
MADPIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELRPDVVLMDVKMPGMDGVDALRKLRELDNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEDTSSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=652070 OHT76_RS09840 WP_328870379.1 2160536..2161177(-) (vraR) [Streptomyces sp. NBC_00287]
GTGGCTGACCCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGCACATTCCTCGAAGTACA
GGACGACATCGAGGTCGTGGGCGAGGCCGCCGACGGGGCCGAGGGAGTCGCCCGTGCCGAGGAGCTGCGGCCCGACGTCG
TCCTGATGGACGTCAAGATGCCGGGCATGGACGGCGTCGACGCCCTGCGCAAGCTCCGCGAGCTGGACAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAACAGCGCACGGTGGTCCCGGCCCTGCGCGCCGGTGCCGCCGGTTACGTCTACAA
GGATGTCGACCCCGACGCCCTGGCCGGCGCCATCCGCTCCGTCCACGCCGGGCACATCCTGCTCCAGCCCGAGGTCGCCG
GGGCCCTGCTGTCCCAGGAGGACACGAGCTCAGGACAGGGCAGGGGCGGTTCGCTGACCGAACGGGAGCGCGAGGTGCTC
GGCCTGATAGCGGACGGCCGCTCCAACCGGGAGATCGCCCGCGCGCTGGTGCTCTCCGAGAAGACGGTGAAGACGCATGT
GTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGCACACAGGCGGCACTGTGGGCGGTACGGCACGGTGTGGCCGGAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.89

98.122

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399