Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG985_RS38315 Genome accession   NZ_CP108046
Coordinates   8459050..8459712 (-) Length   220 a.a.
NCBI ID   WP_371672965.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00289     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8454050..8464712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG985_RS38295 (OG985_38190) - 8454632..8455474 (-) 843 WP_371672961.1 alpha/beta fold hydrolase -
  OG985_RS38300 (OG985_38195) - 8455817..8456695 (+) 879 WP_371672962.1 RNA polymerase sigma-70 factor -
  OG985_RS38305 (OG985_38200) - 8456940..8457701 (+) 762 WP_371672963.1 GntR family transcriptional regulator -
  OG985_RS38310 (OG985_38205) - 8457783..8458940 (-) 1158 WP_371672964.1 ROK family transcriptional regulator -
  OG985_RS38315 (OG985_38210) vraR 8459050..8459712 (-) 663 WP_371672965.1 response regulator Regulator
  OG985_RS38320 (OG985_38215) - 8459727..8460902 (-) 1176 WP_371672966.1 sensor histidine kinase -
  OG985_RS38325 (OG985_38220) - 8461011..8461946 (+) 936 WP_371672967.1 ABC transporter ATP-binding protein -
  OG985_RS38330 (OG985_38225) - 8461948..8462673 (+) 726 WP_371672968.1 ABC transporter permease -
  OG985_RS38335 (OG985_38230) - 8462732..8463178 (+) 447 WP_371672969.1 hypothetical protein -
  OG985_RS38340 (OG985_38235) mug 8463190..8463762 (-) 573 WP_371674613.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23619.22 Da        Isoelectric Point: 5.1637

>NTDB_id=652039 OG985_RS38315 WP_371672965.1 8459050..8459712(-) (vraR) [Streptomyces sp. NBC_00289]
MPVTVLLVDDEPLVRAGLRAVLESQPDIEVVGEAADGAAVIPLVRRLRPDVVAMDVRMPLMDGIEATRAVLRTVDEPPKI
LVVTTFENDEYVYDALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRRLAAEYGDHGANRAAHAAMERAQLTDR
EAEVLRLMARGLSNAEIAARLIVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=652039 OG985_RS38315 WP_371672965.1 8459050..8459712(-) (vraR) [Streptomyces sp. NBC_00289]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAGCCCCTCGTCCGCGCCGGTCTGCGCGCCGTGCTGGAGTCGCAGCCCGA
CATCGAGGTCGTCGGAGAGGCGGCCGACGGCGCGGCGGTGATTCCCCTGGTGCGGCGGCTGCGGCCGGACGTGGTCGCCA
TGGACGTACGGATGCCCCTCATGGACGGCATCGAGGCCACGCGCGCGGTGCTGCGGACGGTCGACGAGCCGCCGAAGATC
CTCGTCGTGACGACCTTCGAGAACGACGAGTACGTGTACGACGCACTGCGGGCCGGGGCGGACGGGTTCCTGCTGAAGCG
GGCCCGGCCCGCCGAGATCGTGCACGCCGTGCGGCTGGTCGCCGAGGGCGAGTCGCTGCTCTTCCCGGCCTCGGTGCGGC
GGCTCGCCGCCGAGTACGGCGACCACGGCGCGAACCGCGCGGCCCACGCCGCGATGGAACGGGCCCAGCTCACCGACCGC
GAGGCGGAGGTGCTGCGGCTGATGGCCCGCGGGCTGTCGAACGCCGAGATCGCCGCCCGGCTGATCGTCGGGACCGAGAC
CGTGAAGTCCCATGTGAGCGCCGTGCTGGCGAAGCTGGGGGCGCGGGATCGCACGCAGGCCGTGATCGCGGCGTACGAGT
CGGGGTTCGTCGCGCCGGGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.743

99.091

0.414
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.382