Detailed information NTG0065181

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SPYJRS4_RS03370
• Genome accession: NZ_AP012335
• Coordinates: 671688..672917 (+)
• Length: 409 a.a.
• NCBI ID: WP_060823524.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes JRS4
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 666688..677917

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYJRS4_RS03350 (SPYJRS4_0686)	-	667304..668581 (-)	1278	WP_011184410.1	hydroxymethylglutaryl-CoA reductase, degradative	-
SPYJRS4_RS03355 (SPYJRS4_0687)	-	668568..669743 (-)	1176	WP_021340258.1	hydroxymethylglutaryl-CoA synthase	-
SPYJRS4_RS03360 (SPYJRS4_0688)	-	669952..670791 (+)	840	WP_011017679.1	thymidylate synthase	-
SPYJRS4_RS03365 (SPYJRS4_0689)	-	670871..671368 (+)	498	WP_011184412.1	dihydrofolate reductase	-
SPYJRS4_RS09090 (SPYJRS4_0690)	-	671388..671558 (+)	171	WP_002990165.1	hypothetical protein	-
SPYJRS4_RS03370 (SPYJRS4_0691)	clpX	671688..672917 (+)	1230	WP_060823524.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SPYJRS4_RS03375 (SPYJRS4_0692)	yihA	672927..673526 (+)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SPYJRS4_RS03380 (SPYJRS4_0693)	-	673674..674417 (+)	744	WP_002984942.1	hypothetical protein	-
SPYJRS4_RS03385 (SPYJRS4_0694)	-	674475..676574 (-)	2100	WP_011184415.1	ATP-dependent Clp protease ATP-binding subunit	-
SPYJRS4_RS03390 (SPYJRS4_0695)	rpiA	676953..677636 (+)	684	WP_011184416.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44980.41 Da
• Isoelectric Point: 4.6184

>NTDB_id=65181 SPYJRS4_RS03370 WP_060823524.1 671688..672917(+) (clpX) [Streptococcus pyogenes JRS4]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVASSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=65181 SPYJRS4_RS03370 WP_060823524.1 671688..672917(+) (clpX) [Streptococcus pyogenes JRS4]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTCATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCTAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGCTTGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577