Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA05_RS29275 Genome accession   NZ_CP108032
Coordinates   6567671..6568342 (+) Length   223 a.a.
NCBI ID   WP_313943291.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00306     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6562671..6573342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA05_RS29245 (OHA05_29255) alc 6562695..6563813 (+) 1119 WP_313948815.1 allantoicase -
  OHA05_RS29250 (OHA05_29260) - 6564061..6564789 (-) 729 WP_313943296.1 SDR family oxidoreductase -
  OHA05_RS29255 (OHA05_29265) - 6565018..6565632 (+) 615 WP_328862158.1 dihydrofolate reductase family protein -
  OHA05_RS29260 (OHA05_29270) - 6565669..6566043 (+) 375 WP_313943294.1 hypothetical protein -
  OHA05_RS29265 (OHA05_29275) - 6566086..6566298 (-) 213 WP_328862159.1 hypothetical protein -
  OHA05_RS29270 (OHA05_29280) - 6566445..6567674 (+) 1230 WP_313943292.1 histidine kinase -
  OHA05_RS29275 (OHA05_29285) vraR 6567671..6568342 (+) 672 WP_313943291.1 response regulator transcription factor Regulator
  OHA05_RS29280 (OHA05_29290) - 6568352..6569530 (+) 1179 WP_328862160.1 cytochrome P450 -
  OHA05_RS29285 (OHA05_29295) - 6569627..6570046 (+) 420 WP_313943289.1 PaaI family thioesterase -
  OHA05_RS29290 (OHA05_29300) - 6570188..6571192 (-) 1005 WP_313943288.1 Gfo/Idh/MocA family oxidoreductase -
  OHA05_RS29295 (OHA05_29305) - 6571348..6572067 (+) 720 WP_328863475.1 GntR family transcriptional regulator -
  OHA05_RS29300 (OHA05_29310) - 6572229..6573227 (+) 999 WP_313943287.1 sugar ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23885.34 Da        Isoelectric Point: 4.7530

>NTDB_id=651796 OHA05_RS29275 WP_313943291.1 6567671..6568342(+) (vraR) [Streptomyces sp. NBC_00306]
MTIRLLVVDDDPLVRAGLSFMLGGADDLEIVGEGADGSEVPELIDRLSPDVVLMDIRMPTVDGLRATEELRRRPDAPEVV
VLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVAAVRRVASGDPVLSPAVTRQLMSHVADRVPDPRRSTAAQRLDSLAER
EREVAVAVGRGQSNAEIAATLYMSVPTVKTHVSRILAKLDLNNRVQIALLAHDAGLLDGEGPT

Nucleotide


Download         Length: 672 bp        

>NTDB_id=651796 OHA05_RS29275 WP_313943291.1 6567671..6568342(+) (vraR) [Streptomyces sp. NBC_00306]
ATGACTATCCGGTTGCTCGTCGTCGATGACGACCCCCTGGTCCGGGCGGGCCTCTCCTTCATGCTCGGCGGGGCCGACGA
CCTCGAGATCGTCGGGGAGGGCGCGGACGGTTCCGAGGTACCGGAACTGATCGACCGGCTCTCGCCCGACGTCGTGCTGA
TGGACATCCGGATGCCGACGGTGGACGGACTGCGCGCCACCGAGGAGCTGCGGCGCAGGCCCGACGCCCCCGAGGTCGTG
GTGCTCACCACGTTCCACGCGGACGAGCAGGTGCTGCGGGCGCTGCGGGCCGGGGCCGCCGGGTTCGTCCTCAAGGACAC
CCCGCCGGCCGAGATCGTCGCCGCGGTGCGGCGGGTGGCTTCCGGGGACCCGGTGCTCTCCCCGGCCGTGACCCGCCAGC
TGATGTCGCACGTCGCCGACCGGGTGCCCGACCCGCGCCGCAGCACGGCGGCCCAGCGGCTGGACTCGCTCGCGGAACGG
GAGCGGGAGGTGGCGGTCGCGGTGGGCCGCGGCCAGTCCAACGCGGAGATCGCGGCGACGCTGTACATGAGCGTGCCGAC
CGTGAAGACCCATGTGTCGCGCATCCTCGCGAAGCTGGATCTCAACAACCGTGTCCAGATCGCGCTGCTCGCGCACGACG
CTGGCCTGCTGGACGGGGAGGGGCCGACGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.788

97.309

0.368