Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA05_RS11025 Genome accession   NZ_CP108032
Coordinates   2488703..2489386 (+) Length   227 a.a.
NCBI ID   WP_328860460.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00306     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2483703..2494386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA05_RS11005 (OHA05_11025) - 2484234..2484911 (+) 678 WP_313946510.1 TetR family transcriptional regulator -
  OHA05_RS11010 (OHA05_11030) - 2485131..2486342 (+) 1212 WP_328860457.1 alpha/beta hydrolase -
  OHA05_RS11015 (OHA05_11035) - 2486418..2487284 (+) 867 WP_328860458.1 DUF4429 domain-containing protein -
  OHA05_RS11020 (OHA05_11040) - 2487387..2488706 (+) 1320 WP_328860459.1 sensor histidine kinase -
  OHA05_RS11025 (OHA05_11045) vraR 2488703..2489386 (+) 684 WP_328860460.1 response regulator transcription factor Regulator
  OHA05_RS11030 (OHA05_11050) - 2489627..2490703 (+) 1077 WP_328860461.1 alpha/beta hydrolase -
  OHA05_RS11035 (OHA05_11055) - 2490700..2491890 (+) 1191 WP_328860462.1 acyltransferase -
  OHA05_RS11040 (OHA05_11060) - 2491960..2492976 (-) 1017 WP_328860463.1 aldo/keto reductase -
  OHA05_RS11045 (OHA05_11065) - 2492983..2493438 (-) 456 WP_313946502.1 MerR family transcriptional regulator -
  OHA05_RS11050 (OHA05_11070) - 2493524..2493985 (+) 462 WP_328860464.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24280.07 Da        Isoelectric Point: 5.6507

>NTDB_id=651741 OHA05_RS11025 WP_328860460.1 2488703..2489386(+) (vraR) [Streptomyces sp. NBC_00306]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGRAGVDVARSTHPDVVLMDVRMPEMDGLTAARELLHPPVGVVHV
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGEALLAPSVTRRLITEFASQRQAPRKDPSLRLNGL
TPRETEVLELIARGLSNQEIAAHLVLAEQTVKTHIGRVLSKLALRDRAQAVIFAYESGLVRPGAADS

Nucleotide


Download         Length: 684 bp        

>NTDB_id=651741 OHA05_RS11025 WP_328860460.1 2488703..2489386(+) (vraR) [Streptomyces sp. NBC_00306]
GTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGCTTCGCCGCGCTGCTGGCGGCGCAGTCCGA
CATCGACGTGGTGGGCGAGGCGCCGGACGGCCGGGCGGGCGTGGACGTGGCGCGGTCCACGCACCCCGACGTGGTGCTGA
TGGACGTCCGGATGCCGGAGATGGACGGCCTGACCGCCGCCCGCGAGCTCCTCCACCCGCCGGTGGGAGTCGTGCATGTG
CCCAAGGTGCTGATGCTGACCACCTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGGGCGGGTGCGTCCGGGTTCCT
GCTGAAGGACGCGCCCCCGGCGGATCTGATCGCGGCGGTACGGGTGGTGGCGGCGGGCGAGGCGCTGCTGGCCCCCTCGG
TCACCCGCCGGCTGATCACCGAGTTCGCCTCCCAGCGGCAGGCGCCGCGGAAGGACCCCTCCCTGCGGCTGAACGGCCTG
ACCCCGCGCGAGACGGAGGTCCTGGAACTGATCGCGCGCGGTCTGTCCAACCAGGAGATCGCGGCCCATCTGGTGCTGGC
GGAACAGACGGTGAAGACGCACATCGGCAGGGTCCTGTCGAAGCTGGCGCTGCGGGACCGGGCGCAGGCAGTGATCTTCG
CGTACGAATCGGGCCTGGTCCGGCCCGGGGCTGCCGACTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(160-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.704

98.238

0.41
  degU Bacillus subtilis subsp. subtilis str. 168

37.555

100

0.379