Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA05_RS04205 Genome accession   NZ_CP108032
Coordinates   963205..963870 (-) Length   221 a.a.
NCBI ID   WP_313947763.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00306     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 958205..968870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA05_RS04180 (OHA05_04185) - 958615..959835 (+) 1221 WP_328859859.1 MFS transporter -
  OHA05_RS04185 (OHA05_04190) - 959956..960699 (+) 744 WP_328859860.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHA05_RS04190 (OHA05_04195) - 960826..961227 (-) 402 WP_313947767.1 MarR family transcriptional regulator -
  OHA05_RS04195 (OHA05_04200) - 961314..962795 (+) 1482 WP_328859861.1 MFS transporter -
  OHA05_RS04200 (OHA05_04205) - 962960..963244 (+) 285 WP_313947764.1 DUF6332 family protein -
  OHA05_RS04205 (OHA05_04210) vraR 963205..963870 (-) 666 WP_313947763.1 response regulator transcription factor Regulator
  OHA05_RS04210 (OHA05_04215) - 963867..965111 (-) 1245 WP_313947762.1 histidine kinase -
  OHA05_RS04215 (OHA05_04220) - 965315..966031 (-) 717 WP_328859862.1 TetR/AcrR family transcriptional regulator -
  OHA05_RS04220 (OHA05_04225) - 966216..966665 (+) 450 WP_328859863.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHA05_RS04225 (OHA05_04230) - 966942..968210 (-) 1269 WP_313947759.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24177.98 Da        Isoelectric Point: 4.7422

>NTDB_id=651729 OHA05_RS04205 WP_313947763.1 963205..963870(-) (vraR) [Streptomyces sp. NBC_00306]
MIRVLLADDQLLVRAGFRALLDAQQDIEVAGEAADGEEAVRLVRELTPDVVLMDIRMPLLDGLAATRRITGDERLHDVKV
VMLTTFELDEYVFEAIRAGASGFLVKDTEPEELLRAVRAVVAGDALLSPGVTRRLIAEFAARSKEPKDAEGLGELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=651729 OHA05_RS04205 WP_313947763.1 963205..963870(-) (vraR) [Streptomyces sp. NBC_00306]
GTGATCCGCGTACTGCTCGCCGATGACCAGCTGTTGGTCCGAGCCGGGTTCAGGGCCCTGCTGGACGCCCAGCAGGACAT
CGAGGTGGCCGGTGAGGCCGCCGACGGCGAGGAGGCGGTGCGGCTGGTGCGCGAACTGACCCCGGACGTCGTGCTGATGG
ACATCCGGATGCCCCTGCTCGACGGGCTCGCGGCCACCCGCAGGATCACCGGCGACGAGCGGCTCCACGACGTGAAGGTC
GTCATGCTGACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCGCCGGCGCCTCGGGCTTTCTGGTGAAGGA
CACCGAACCGGAGGAACTGCTGCGCGCGGTACGGGCGGTGGTGGCCGGCGACGCCCTGCTGTCGCCCGGGGTGACGCGGC
GTCTGATCGCGGAGTTCGCGGCCCGTTCCAAGGAGCCGAAGGACGCGGAGGGCCTCGGTGAACTCACCGAGCGCGAACGC
GAGGTGATGGCCCTGGTCGGTATCGGCCTGTCGAACGAGGAGATCGCGCGCCGGCTGGTCGTCAGTCCTCTGACGGCCAA
GACGCACGTCAGCCGCACGATGGTGAAACTGGGGGCCCGCGACCGGGCCCAACTCGTCGTCCTGGCCTATGAGTCGGGGT
TGGTGCGGCCCGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.535

97.285

0.385
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.367