Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB47_RS09670 Genome accession   NZ_CP108030
Coordinates   2132729..2133379 (+) Length   216 a.a.
NCBI ID   WP_266722225.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00311     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2127729..2138379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB47_RS09645 (OHB47_09655) mug 2128268..2128816 (+) 549 WP_327675368.1 G/U mismatch-specific DNA glycosylase -
  OHB47_RS09650 (OHB47_09660) - 2128826..2129623 (-) 798 WP_327664485.1 SAM-dependent methyltransferase -
  OHB47_RS09655 (OHB47_09665) - 2129709..2130452 (-) 744 WP_327675370.1 ABC transporter permease -
  OHB47_RS09660 (OHB47_09670) - 2130465..2131388 (-) 924 WP_327669365.1 ATP-binding cassette domain-containing protein -
  OHB47_RS09665 (OHB47_09675) - 2131497..2132714 (+) 1218 WP_327664483.1 histidine kinase -
  OHB47_RS09670 (OHB47_09680) vraR 2132729..2133379 (+) 651 WP_266722225.1 response regulator transcription factor Regulator
  OHB47_RS09675 (OHB47_09685) - 2133533..2134690 (+) 1158 WP_327669366.1 ROK family protein -
  OHB47_RS09680 (OHB47_09690) - 2134740..2135501 (-) 762 WP_327669367.1 GntR family transcriptional regulator -
  OHB47_RS09685 (OHB47_09695) sigJ 2135727..2136608 (-) 882 WP_327669368.1 RNA polymerase sigma factor SigJ -
  OHB47_RS09690 (OHB47_09700) - 2136790..2137620 (+) 831 WP_327664479.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22982.60 Da        Isoelectric Point: 4.9855

>NTDB_id=651642 OHB47_RS09670 WP_266722225.1 2132729..2133379(+) (vraR) [Streptomyces sp. NBC_00311]
MPLTVLLVDDEPLVRAGLRAVLEAQPDITVVGEAADGAAVVPLVRELRPDVVAMDVRMPLLDGIEATRAVLRGAERPPKI
LVITTFENDEYVYGALRAGADGFLLKRARPEEIVHAVRLVAAGESLLFPAAVRKLAAEYGSSVARAALERAALTEREEQV
LRLMARGLSNAEIAADLVVGTETVKSHVSAVLTKLGARDRTQAVIAAYESGFVAPS

Nucleotide


Download         Length: 651 bp        

>NTDB_id=651642 OHB47_RS09670 WP_266722225.1 2132729..2133379(+) (vraR) [Streptomyces sp. NBC_00311]
GTGCCGCTCACCGTGCTTCTTGTCGACGACGAACCGCTCGTCCGCGCGGGCCTGCGCGCGGTGCTCGAAGCGCAGCCGGA
CATCACGGTGGTGGGTGAGGCCGCGGACGGCGCGGCGGTCGTGCCCCTGGTCCGCGAGCTGCGACCCGACGTGGTCGCCA
TGGACGTCCGGATGCCGCTGCTCGACGGGATCGAGGCCACGCGCGCGGTGCTGCGCGGCGCGGAGCGGCCGCCGAAGATC
CTCGTGATCACCACGTTCGAGAACGACGAGTACGTGTACGGGGCGCTGCGCGCGGGCGCCGACGGCTTCCTCCTGAAGCG
GGCACGCCCCGAGGAGATCGTGCACGCGGTGCGCCTCGTCGCGGCGGGCGAGTCGCTCCTGTTCCCGGCCGCGGTCCGCA
AGTTGGCGGCGGAGTACGGGAGTTCGGTGGCCCGTGCGGCCCTGGAGCGCGCGGCGCTGACCGAACGCGAGGAGCAGGTG
CTGCGGCTCATGGCGCGCGGCCTGTCGAACGCGGAGATCGCCGCGGACCTGGTCGTCGGCACCGAGACGGTCAAGTCCCA
CGTGAGCGCGGTGCTGACGAAGCTGGGCGCGCGGGACCGGACGCAGGCCGTGATCGCGGCGTACGAGTCGGGGTTCGTGG
CGCCGAGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.589

99.074

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

34.956

100

0.366