Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG878_RS11215 Genome accession   NZ_CP108023
Coordinates   2535873..2536553 (-) Length   226 a.a.
NCBI ID   WP_328886647.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00316     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2530873..2541553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG878_RS11195 (OG878_11220) - 2531315..2532985 (+) 1671 WP_328886643.1 sensor histidine kinase -
  OG878_RS11200 (OG878_11225) - 2532982..2533659 (+) 678 WP_328886644.1 response regulator -
  OG878_RS11205 (OG878_11230) - 2533709..2535301 (-) 1593 WP_328886645.1 cation acetate symporter -
  OG878_RS11210 (OG878_11235) - 2535298..2535774 (-) 477 WP_328886646.1 DUF485 domain-containing protein -
  OG878_RS11215 (OG878_11240) vraR 2535873..2536553 (-) 681 WP_328886647.1 response regulator transcription factor Regulator
  OG878_RS11220 (OG878_11245) - 2536550..2537713 (-) 1164 WP_328886648.1 sensor histidine kinase -
  OG878_RS11225 (OG878_11250) - 2537710..2538222 (-) 513 WP_328886649.1 DUF1453 domain-containing protein -
  OG878_RS11230 (OG878_11255) - 2538355..2540475 (-) 2121 WP_328886650.1 DNA topoisomerase IV subunit B -
  OG878_RS11235 (OG878_11260) - 2540911..2541144 (+) 234 WP_328886651.1 hypothetical protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 23938.43 Da        Isoelectric Point: 5.3732

>NTDB_id=651571 OG878_RS11215 WP_328886647.1 2535873..2536553(-) (vraR) [Streptomyces sp. NBC_00316]
MSARVVVADDQSVVREGIVMLLGLLPGIEVVGSAKDGEEAVALVAEKAPDVVLMDLRMPRCDGVEATRRIRAEYPNTQVV
VLTTFAEDDSLFPALQAGARGYLTKDAGGEEIARAIQAVLSGEAGFSPTVQRRLLERVTTAPAPAGPRAGEPLLPDGLTP
REAEVLVLIADGLSNPEIARALHISQATVKSHINNLFAKAGLRDRAQAVRYAYVRGLAHPPGTSFT

Nucleotide


Download         Length: 681 bp        

>NTDB_id=651571 OG878_RS11215 WP_328886647.1 2535873..2536553(-) (vraR) [Streptomyces sp. NBC_00316]
GTGAGCGCGCGGGTCGTGGTCGCCGACGATCAGTCGGTGGTGCGCGAGGGAATCGTGATGCTGTTGGGACTGCTGCCCGG
AATCGAGGTGGTGGGATCGGCGAAGGACGGGGAAGAGGCCGTTGCGCTCGTCGCCGAGAAGGCCCCGGACGTGGTCCTGA
TGGACCTCCGCATGCCGCGCTGCGACGGAGTGGAGGCGACGCGGCGGATCCGCGCGGAGTATCCGAACACCCAGGTGGTG
GTTCTCACGACGTTCGCGGAGGACGACTCGCTCTTCCCCGCGCTGCAGGCGGGTGCCCGCGGATATCTCACCAAGGACGC
CGGGGGCGAGGAGATCGCGCGGGCGATCCAGGCGGTGCTGTCGGGCGAGGCCGGATTCTCGCCCACGGTGCAGCGGCGGT
TGCTGGAGCGGGTCACCACGGCACCCGCGCCGGCCGGACCGCGGGCCGGCGAGCCCCTGCTGCCCGACGGCCTCACGCCG
CGTGAGGCGGAAGTGCTCGTCCTGATCGCCGACGGACTGTCGAATCCGGAGATCGCCCGCGCGCTGCACATCTCGCAGGC
CACCGTGAAAAGCCACATCAACAATCTCTTCGCCAAGGCCGGACTGCGCGACAGGGCACAAGCTGTGCGCTATGCGTACG
TTCGGGGTCTCGCACACCCGCCCGGGACATCCTTCACCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.475

96.018

0.398
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

99.558

0.363