Detailed information NTG0651350

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L3475_RS09380
• Genome accession: NZ_CP091451
• Coordinates: 1816996..1818033 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 3238/09
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1811996..1823033

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3475_RS09355 (L3475_09280)	-	1812735..1814066 (-)	1332	WP_000390039.1	hemolysin family protein	-
L3475_RS09360 (L3475_09285)	endA	1814357..1815181 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
L3475_RS09365 (L3475_09290)	-	1815220..1815408 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
L3475_RS09370 (L3475_09295)	murA	1815401..1816684 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
L3475_RS09375 (L3475_09300)	-	1816708..1816938 (-)	231	WP_000615437.1	DUF1146 family protein	-
L3475_RS09380 (L3475_09305)	sepM	1816996..1818033 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
L3475_RS09385 (L3475_09310)	coaD	1818017..1818505 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
L3475_RS09390 (L3475_09315)	rsmD	1818495..1819034 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L3475_RS09395 (L3475_09320)	asnA	1819099..1820091 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
L3475_RS09400 (L3475_09325)	-	1820203..1820886 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
L3475_RS09405 (L3475_09330)	-	1820942..1821682 (-)	741	WP_000152701.1	RNA methyltransferase	-
L3475_RS09410 (L3475_09335)	-	1821716..1821994 (+)	279	WP_001174613.1	acylphosphatase	-
L3475_RS09415 (L3475_09340)	yidC	1822072..1822998 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=651350 L3475_RS09380 WP_000727280.1 1816996..1818033(-) (sepM) [Streptococcus pneumoniae strain 3238/09]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=651350 L3475_RS09380 WP_000727280.1 1816996..1818033(-) (sepM) [Streptococcus pneumoniae strain 3238/09]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591