Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB16_RS19075 Genome accession   NZ_CP108008
Coordinates   4110984..4111649 (+) Length   221 a.a.
NCBI ID   WP_271319458.1    Uniprot ID   A0ABV9WUH6
Organism   Streptomyces sp. NBC_00334     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4105984..4116649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB16_RS19055 (OHB16_19070) - 4106214..4107419 (+) 1206 WP_328658544.1 acyltransferase -
  OHB16_RS19060 (OHB16_19075) - 4107412..4108866 (+) 1455 WP_328658546.1 sensor histidine kinase -
  OHB16_RS19065 (OHB16_19080) vraR 4108863..4109549 (+) 687 WP_271319456.1 response regulator transcription factor Regulator
  OHB16_RS19070 (OHB16_19085) - 4109563..4110987 (+) 1425 WP_271319457.1 histidine kinase -
  OHB16_RS19075 (OHB16_19090) vraR 4110984..4111649 (+) 666 WP_271319458.1 response regulator transcription factor Regulator
  OHB16_RS19080 (OHB16_19095) - 4111619..4112056 (-) 438 WP_271319459.1 ATP-binding protein -
  OHB16_RS19085 (OHB16_19100) - 4112280..4113131 (+) 852 WP_271319460.1 helix-turn-helix transcriptional regulator -
  OHB16_RS19090 (OHB16_19105) - 4113131..4113319 (+) 189 WP_271319461.1 DUF397 domain-containing protein -
  OHB16_RS19095 (OHB16_19110) - 4113353..4113532 (+) 180 WP_271319462.1 DUF397 domain-containing protein -
  OHB16_RS19100 (OHB16_19115) - 4113596..4114825 (+) 1230 WP_328658549.1 cytochrome P450 -
  OHB16_RS19105 (OHB16_19120) - 4114808..4115074 (-) 267 WP_271319464.1 hypothetical protein -
  OHB16_RS19110 (OHB16_19125) - 4115142..4115606 (-) 465 WP_328658551.1 cupin domain-containing protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23810.59 Da        Isoelectric Point: 4.7315

>NTDB_id=651350 OHB16_RS19075 WP_271319458.1 4110984..4111649(+) (vraR) [Streptomyces sp. NBC_00334]
MTIRVLIADDQMMVREGFSVLLNAMPGIEVVGEAVNGREAVAKVRELAPDVVLMDIRMPELNGIEATREIVAADGAAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPSVTKRLITEFSKLSDTPRLMPSAQAAYGDLTE
RETEVLVLIAQGMSNSEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=651350 OHB16_RS19075 WP_271319458.1 4110984..4111649(+) (vraR) [Streptomyces sp. NBC_00334]
ATGACGATCCGCGTACTGATCGCCGACGACCAGATGATGGTGCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGG
CATCGAGGTCGTTGGTGAGGCGGTCAACGGCCGGGAGGCGGTGGCGAAGGTCCGCGAGCTCGCCCCGGACGTCGTCTTGA
TGGACATCCGCATGCCCGAGTTGAACGGCATCGAGGCGACGCGGGAGATCGTGGCGGCCGACGGTGCGGCGAAGGTGCTG
GTGCTCACCACCTTCGATCTCGACGAGTACGTCTACCAGGCGCTGCGCGCCGGGGCGTCCGGCTTCCTCCTGAAGGACGC
TTCGGCCCGCCAGCTCGCCGACGGCGTCCGGGTGGTGGCGTCCGGCGAGGCCCTCCTGGCCCCCTCGGTCACCAAGCGCC
TCATCACCGAGTTCTCCAAGCTGTCCGACACCCCGCGCCTGATGCCCTCGGCCCAGGCGGCGTACGGCGACCTCACCGAG
CGCGAGACGGAGGTCCTGGTCCTGATCGCGCAGGGCATGTCCAACTCGGAGATCGCCGAGCGGTTGGTGGTCGCCGAGTC
GACGATCAAGACCCACGTCAGCCGCATCCTGGTGAAGCTGGGCCTGCGCGACCGTACCCAGGCGGCGGTCTTCGCCTACG
AGGCGCGGCTGGTGACGCCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.495

98.643

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

42.857

98.19

0.421