Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB16_RS05230 Genome accession   NZ_CP108008
Coordinates   1139215..1139877 (+) Length   220 a.a.
NCBI ID   WP_271414742.1    Uniprot ID   A0ABV9X143
Organism   Streptomyces sp. NBC_00334     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1134215..1144877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB16_RS05205 (OHB16_05215) mug 1135247..1135756 (+) 510 WP_328661324.1 G/U mismatch-specific DNA glycosylase -
  OHB16_RS05210 (OHB16_05220) - 1135766..1136206 (-) 441 WP_328656428.1 hypothetical protein -
  OHB16_RS05215 (OHB16_05225) - 1136277..1137002 (-) 726 WP_328656430.1 ABC transporter permease -
  OHB16_RS05220 (OHB16_05230) - 1137005..1137925 (-) 921 WP_271414740.1 ATP-binding cassette domain-containing protein -
  OHB16_RS05225 (OHB16_05235) - 1138034..1139200 (+) 1167 WP_328656433.1 histidine kinase -
  OHB16_RS05230 (OHB16_05240) vraR 1139215..1139877 (+) 663 WP_271414742.1 response regulator transcription factor Regulator
  OHB16_RS05235 (OHB16_05245) - 1139977..1141131 (+) 1155 WP_271414743.1 ROK family transcriptional regulator -
  OHB16_RS05240 (OHB16_05250) - 1141351..1142112 (-) 762 WP_271414744.1 GntR family transcriptional regulator -
  OHB16_RS05245 (OHB16_05255) - 1142356..1143225 (-) 870 WP_271414745.1 alpha/beta fold hydrolase -
  OHB16_RS05250 (OHB16_05260) - 1143557..1144216 (+) 660 WP_271414746.1 HD domain-containing protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23519.16 Da        Isoelectric Point: 5.4441

>NTDB_id=651319 OHB16_RS05230 WP_271414742.1 1139215..1139877(+) (vraR) [Streptomyces sp. NBC_00334]
MPVRVLLVDDEPLVRAGLRAVLEAQPDIEVAGEAADGAAVIPLVRQVRPDVVAMDVRMPLLDGIEATRALLRTVADPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLIAEGESLLFPASVRRLAAEYGDGGGNRAARAALERARLTER
EGEVLRLMARGLSNAEIAARLVVGTETVKSHVSAVLAKLAARDRTQAVITAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=651319 OHB16_RS05230 WP_271414742.1 1139215..1139877(+) (vraR) [Streptomyces sp. NBC_00334]
ATGCCGGTCAGAGTGCTCCTCGTCGACGACGAACCCCTGGTGCGCGCCGGTCTGCGGGCCGTGCTGGAGGCGCAGCCGGA
CATCGAGGTGGCCGGGGAGGCCGCCGACGGGGCGGCGGTCATTCCGCTGGTGCGGCAGGTGCGGCCGGACGTGGTGGCCA
TGGACGTCCGCATGCCGCTGCTCGACGGGATCGAGGCCACGCGCGCGCTGCTGCGGACGGTGGCCGACCCGCCGAAGATC
CTGGTGGTGACGACCTTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGGGCCGGCGCCGACGGGTTCCTGCTCAAGCG
GGCCCGCCCGGCGGAGATCGTGCACGCGGTGCGGCTGATCGCCGAGGGCGAGTCCCTGCTGTTCCCCGCCTCGGTGCGGC
GGCTCGCCGCCGAGTACGGCGACGGCGGCGGCAACCGCGCGGCCCGCGCCGCCCTGGAGCGCGCCCGGCTGACCGAGCGG
GAGGGCGAGGTGCTGCGGTTGATGGCGCGGGGGCTGTCGAACGCCGAGATCGCCGCCCGGCTGGTCGTCGGCACGGAGAC
GGTGAAGTCGCACGTGAGCGCCGTACTGGCGAAGCTGGCGGCCCGGGACCGCACGCAGGCGGTGATCACGGCGTACGAGT
CGGGGTTCGTGGCACCCGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.639

99.545

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.364