Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   L3474_RS01860 Genome accession   NZ_CP091450
Coordinates   350730..351419 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 3641/15     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 345730..356419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3474_RS01835 (L3474_01805) gpsB 345815..346156 (+) 342 WP_000200644.1 cell division regulator GpsB -
  L3474_RS01845 (L3474_01815) - 346642..347799 (+) 1158 WP_000711397.1 class I SAM-dependent RNA methyltransferase -
  L3474_RS01850 (L3474_01820) mapZ 347812..349218 (+) 1407 WP_000039266.1 mid-cell-anchored protein MapZ -
  L3474_RS01855 (L3474_01825) gndA 349294..350718 (+) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  L3474_RS01860 (L3474_01830) covR 350730..351419 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  L3474_RS01865 (L3474_01835) - 351518..352573 (+) 1056 WP_001839256.1 N-acetylmuramoyl-L-alanine amidase family protein -
  L3474_RS01870 (L3474_01840) - 352950..356240 (+) 3291 WP_001009805.1 SHIRT domain-containing protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=651234 L3474_RS01860 WP_000518011.1 350730..351419(+) (covR) [Streptococcus pneumoniae strain 3641/15]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=651234 L3474_RS01860 WP_000518011.1 350730..351419(+) (covR) [Streptococcus pneumoniae strain 3641/15]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTCGGTTATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467