Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA37_RS10445 Genome accession   NZ_CP108006
Coordinates   2396460..2397149 (+) Length   229 a.a.
NCBI ID   WP_266904058.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00335     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2391460..2402149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA37_RS10425 (OHA37_10430) - 2391645..2393273 (+) 1629 WP_266904055.1 TROVE domain-containing protein -
  OHA37_RS10430 (OHA37_10435) - 2393508..2394533 (+) 1026 WP_266904056.1 adenosine deaminase -
  OHA37_RS10435 (OHA37_10440) - 2394554..2395243 (+) 690 WP_266904057.1 glycerophosphodiester phosphodiesterase -
  OHA37_RS10440 (OHA37_10445) - 2395357..2396463 (+) 1107 WP_266912653.1 histidine kinase -
  OHA37_RS10445 (OHA37_10450) vraR 2396460..2397149 (+) 690 WP_266904058.1 response regulator transcription factor Regulator
  OHA37_RS10450 (OHA37_10455) - 2397296..2398504 (+) 1209 WP_266904059.1 serine hydrolase domain-containing protein -
  OHA37_RS10455 (OHA37_10460) - 2398512..2399057 (-) 546 WP_266904060.1 hypothetical protein -
  OHA37_RS10460 (OHA37_10465) - 2399135..2400313 (-) 1179 WP_266904061.1 spermidine/putrescine ABC transporter substrate-binding protein -
  OHA37_RS10465 (OHA37_10470) - 2400432..2401871 (-) 1440 WP_266904062.1 gamma-aminobutyraldehyde dehydrogenase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 24208.62 Da        Isoelectric Point: 4.5388

>NTDB_id=651227 OHA37_RS10445 WP_266904058.1 2396460..2397149(+) (vraR) [Streptomyces sp. NBC_00335]
MTIRVVVADDQELVRSGFAMILDVQEDIEVVAEVGDGAAAVAAVRSLAPDVALLDVRMPVLDGIEACREISGTSSCRTVM
LTTFDSDEYVYEALHAGASGFLLKDVRRDDLVHAVRVVAAGESLLAPSVARRLIAEYTAATARPAAGEALSAERLEVLTA
RERETLLHLGRGLSNAELAVELMVSEHTVKSHVGNVLSKLGLRDRIQAVICAYETGLIAAGSSVSPSGE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=651227 OHA37_RS10445 WP_266904058.1 2396460..2397149(+) (vraR) [Streptomyces sp. NBC_00335]
GTGACGATCCGTGTGGTGGTGGCCGACGACCAGGAACTGGTGCGCAGCGGCTTCGCGATGATCCTGGACGTCCAGGAGGA
CATCGAGGTGGTGGCGGAGGTCGGGGACGGGGCGGCGGCGGTCGCGGCGGTACGGTCCCTCGCGCCCGACGTGGCACTGC
TGGACGTGCGGATGCCCGTGCTGGACGGGATCGAGGCGTGCCGGGAGATCTCGGGGACGAGTTCCTGCCGGACGGTGATG
CTGACGACCTTCGACTCGGACGAGTACGTGTACGAGGCGCTGCACGCGGGGGCCAGCGGGTTCCTGCTCAAGGACGTGCG
GCGGGACGATCTGGTGCACGCCGTACGGGTGGTGGCGGCGGGCGAGTCCCTGCTGGCGCCTTCGGTGGCCCGGCGGCTGA
TCGCGGAGTACACGGCGGCGACGGCCCGGCCGGCGGCCGGGGAGGCGCTGTCCGCGGAGCGGCTGGAGGTCCTGACGGCC
CGGGAGCGGGAGACGCTGCTCCACCTGGGGCGGGGGCTGTCGAACGCGGAGCTCGCGGTGGAGCTGATGGTGAGCGAGCA
CACGGTCAAATCGCATGTGGGCAACGTGCTGTCGAAGCTGGGGCTGCGGGACCGGATCCAGGCGGTGATCTGCGCGTACG
AGACGGGTCTGATAGCGGCTGGCTCTTCGGTATCTCCCTCTGGGGAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.096

95.633

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

38.117

97.38

0.371