Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG892_RS22380 Genome accession   NZ_CP108002
Coordinates   4981314..4981964 (-) Length   216 a.a.
NCBI ID   WP_371630090.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00341     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4976314..4986964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG892_RS22355 (OG892_22370) - 4977114..4977686 (+) 573 WP_073732999.1 TetR/AcrR family transcriptional regulator -
  OG892_RS22360 (OG892_22375) - 4978237..4979067 (+) 831 WP_371630088.1 hypothetical protein -
  OG892_RS22365 (OG892_22380) - 4979090..4979401 (-) 312 WP_371630089.1 hypothetical protein -
  OG892_RS22370 (OG892_22385) - 4979582..4980835 (+) 1254 WP_327338265.1 helix-turn-helix transcriptional regulator -
  OG892_RS22375 (OG892_22390) - 4980850..4981215 (+) 366 WP_327338266.1 hypothetical protein -
  OG892_RS22380 (OG892_22395) vraR 4981314..4981964 (-) 651 WP_371630090.1 response regulator Regulator
  OG892_RS22385 (OG892_22400) - 4981999..4983246 (-) 1248 WP_371630091.1 sensor histidine kinase -
  OG892_RS22390 (OG892_22405) - 4983489..4984046 (+) 558 WP_328865985.1 heme-binding protein -
  OG892_RS22395 (OG892_22410) - 4984071..4984667 (+) 597 WP_371630092.1 ankyrin repeat domain-containing protein -
  OG892_RS22400 (OG892_22415) - 4984842..4986206 (+) 1365 WP_371631670.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22970.39 Da        Isoelectric Point: 5.3666

>NTDB_id=651175 OG892_RS22380 WP_371630090.1 4981314..4981964(-) (vraR) [Streptomyces sp. NBC_00341]
MTAAHPPVPTPVRILLCDDHAVVRAGLLALLGSEPDIEVVGEAGSGEEAVALAARLTPDVVLMDLQLGEGIDGVEATRRI
VAGTESAHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSPPVASRVMARMRKPLPTLTDRER
DILGQLSRGLGNRDIARALFISEATVKTHLGRIYDKLDVDTRAGAVAVAKEQRLLP

Nucleotide


Download         Length: 651 bp        

>NTDB_id=651175 OG892_RS22380 WP_371630090.1 4981314..4981964(-) (vraR) [Streptomyces sp. NBC_00341]
ATGACCGCCGCGCACCCGCCCGTCCCCACACCCGTCCGCATCCTGCTCTGCGACGACCACGCCGTCGTACGCGCCGGGCT
CCTCGCCCTCCTGGGCAGCGAGCCGGACATCGAGGTCGTGGGCGAGGCCGGCAGCGGCGAGGAGGCCGTCGCCCTGGCCG
CCCGGCTCACCCCCGACGTCGTCCTGATGGACCTCCAGCTGGGTGAGGGCATCGACGGCGTCGAGGCGACCCGGCGGATC
GTGGCGGGCACGGAAAGCGCCCACGTCCTGGTCCTCACCACGTACGACACGGACGCCGACATCACCCGCGCCATCGAGGC
CGGCGCCACCGGCTACCTGCTGAAGGCCGAGCGCCCGGAGGAGCTCTTCGCCGCGATCCGCTCCGCCGCCCAGGGCCGCA
CCACGCTCTCGCCGCCCGTCGCCAGCCGCGTCATGGCCCGCATGCGCAAGCCGCTGCCCACCCTCACAGACCGCGAACGC
GACATCCTCGGCCAGCTCTCCCGGGGCCTGGGCAACCGCGACATCGCCCGCGCCCTGTTCATCAGCGAGGCCACCGTCAA
GACCCACCTGGGCCGCATCTACGACAAGCTCGACGTCGACACCCGCGCCGGAGCGGTAGCCGTGGCGAAGGAGCAACGGC
TGCTGCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(14-127)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.904

96.296

0.384
  degU Bacillus subtilis subsp. subtilis str. 168

36.364

100

0.37