Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG892_RS11385 Genome accession   NZ_CP108002
Coordinates   2544605..2545291 (+) Length   228 a.a.
NCBI ID   WP_073735871.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00341     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2539605..2550291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG892_RS11365 (OG892_11370) - 2539942..2540595 (+) 654 Protein_2253 TetR/AcrR family transcriptional regulator -
  OG892_RS11370 (OG892_11375) - 2540818..2542029 (+) 1212 WP_371629054.1 alpha/beta hydrolase -
  OG892_RS11375 (OG892_11380) - 2542114..2543067 (+) 954 WP_073735870.1 DUF4429 domain-containing protein -
  OG892_RS11380 (OG892_11385) - 2543189..2544608 (+) 1420 Protein_2256 sensor histidine kinase -
  OG892_RS11385 (OG892_11390) vraR 2544605..2545291 (+) 687 WP_073735871.1 response regulator transcription factor Regulator
  OG892_RS11390 (OG892_11395) - 2545471..2546550 (+) 1080 WP_371629055.1 alpha/beta hydrolase -
  OG892_RS11395 (OG892_11400) - 2546654..2547229 (+) 576 WP_371629056.1 RDD family protein -
  OG892_RS11400 (OG892_11405) - 2547271..2548287 (-) 1017 WP_327336713.1 aldo/keto reductase -
  OG892_RS11405 (OG892_11410) - 2548287..2548754 (-) 468 WP_371629057.1 MerR family transcriptional regulator -
  OG892_RS11410 (OG892_11415) - 2548835..2549650 (+) 816 WP_073735876.1 serine hydrolase -
  OG892_RS11415 (OG892_11420) - 2549616..2550089 (-) 474 WP_371629058.1 ATP-binding protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24195.96 Da        Isoelectric Point: 4.9303

>NTDB_id=651150 OG892_RS11385 WP_073735871.1 2544605..2545291(+) (vraR) [Streptomyces sp. NBC_00341]
MTIRVIIVDDQAMVRAGFAALLAAQADIDVVGEAPDGRQGIDVSRRVHPDVVLMDVRMPEMDGLAAARELLDPPVGVAHV
PRVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGDALLAPSVTRRLIADFARQRPSGAGRGGAALRLN
GLTPRETEVLELIARGLSNQEIAGQLVLAEQTVKTHIGRILAKLDLRDRAQAVIFAYEAGVVVPGESP

Nucleotide


Download         Length: 687 bp        

>NTDB_id=651150 OG892_RS11385 WP_073735871.1 2544605..2545291(+) (vraR) [Streptomyces sp. NBC_00341]
TTGACCATCCGTGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGGTTCGCGGCGCTGCTCGCGGCACAGGCCGA
TATCGATGTGGTCGGTGAGGCGCCGGACGGGCGCCAGGGCATCGACGTCAGCCGCCGGGTCCATCCGGACGTGGTGCTGA
TGGATGTCCGGATGCCCGAGATGGACGGACTGGCGGCGGCACGCGAGCTGCTGGACCCGCCGGTGGGCGTGGCGCACGTG
CCGAGGGTGCTGATGCTGACCACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGTGCGTCCGGCTTCCT
GCTGAAGGACGCGCCCCCGGCGGACCTGATCTCGGCGGTACGGGTGGTGGCGGCGGGTGACGCGCTGCTCGCCCCGTCCG
TGACCCGGCGCCTGATCGCGGACTTCGCCCGCCAACGGCCGTCCGGGGCGGGGCGCGGCGGGGCGGCGCTGCGGCTGAAC
GGGCTGACTCCGCGCGAGACGGAGGTGCTGGAGCTGATAGCCCGGGGGCTGTCGAACCAGGAGATCGCGGGGCAGCTGGT
GCTGGCGGAGCAGACGGTGAAGACGCACATCGGGCGGATACTCGCGAAGCTGGATCTGCGCGACCGGGCCCAGGCGGTGA
TCTTCGCGTACGAGGCGGGCGTGGTGGTACCGGGCGAGAGCCCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.732

98.246

0.39
  degU Bacillus subtilis subsp. subtilis str. 168

37.118

100

0.373