Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA41_RS26695 Genome accession   NZ_CP107999
Coordinates   6000725..6001411 (-) Length   228 a.a.
NCBI ID   WP_073735871.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00342     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5995725..6006411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA41_RS26665 (OHA41_26675) - 5995934..5996407 (+) 474 WP_328696974.1 ATP-binding protein -
  OHA41_RS26670 (OHA41_26680) - 5996373..5997188 (-) 816 WP_328696975.1 serine hydrolase domain-containing protein -
  OHA41_RS26675 (OHA41_26685) - 5997269..5997736 (+) 468 WP_328696976.1 MerR family transcriptional regulator -
  OHA41_RS26680 (OHA41_26690) - 5997736..5998752 (+) 1017 WP_327336713.1 aldo/keto reductase -
  OHA41_RS26685 (OHA41_26695) - 5998788..5999363 (-) 576 WP_328696977.1 RDD family protein -
  OHA41_RS26690 (OHA41_26700) - 5999467..6000546 (-) 1080 WP_328696978.1 alpha/beta hydrolase -
  OHA41_RS26695 (OHA41_26705) vraR 6000725..6001411 (-) 687 WP_073735871.1 response regulator transcription factor Regulator
  OHA41_RS26700 (OHA41_26710) - 6001480..6002808 (-) 1329 WP_328696979.1 sensor histidine kinase -
  OHA41_RS26705 (OHA41_26715) - 6002971..6003933 (-) 963 WP_328696980.1 DUF4429 domain-containing protein -
  OHA41_RS26710 (OHA41_26720) - 6004018..6005229 (-) 1212 WP_327336709.1 alpha/beta hydrolase -
  OHA41_RS26715 (OHA41_26725) - 6005458..6006105 (-) 648 Protein_5270 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24195.96 Da        Isoelectric Point: 4.9303

>NTDB_id=651114 OHA41_RS26695 WP_073735871.1 6000725..6001411(-) (vraR) [Streptomyces sp. NBC_00342]
MTIRVIIVDDQAMVRAGFAALLAAQADIDVVGEAPDGRQGIDVSRRVHPDVVLMDVRMPEMDGLAAARELLDPPVGVAHV
PRVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGDALLAPSVTRRLIADFARQRPSGAGRGGAALRLN
GLTPRETEVLELIARGLSNQEIAGQLVLAEQTVKTHIGRILAKLDLRDRAQAVIFAYEAGVVVPGESP

Nucleotide


Download         Length: 687 bp        

>NTDB_id=651114 OHA41_RS26695 WP_073735871.1 6000725..6001411(-) (vraR) [Streptomyces sp. NBC_00342]
TTGACCATCCGTGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGGTTCGCGGCGCTGCTCGCGGCACAGGCCGA
TATCGATGTGGTCGGTGAGGCGCCGGACGGGCGCCAGGGCATCGACGTCAGCCGCCGGGTCCATCCGGACGTGGTGCTGA
TGGATGTCCGGATGCCCGAGATGGACGGACTGGCGGCGGCACGCGAGCTGCTGGACCCGCCGGTGGGCGTGGCGCACGTG
CCGAGGGTGCTGATGCTGACCACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCGTCCGGCTTCCT
GCTGAAGGACGCGCCCCCGGCGGACCTGATCTCGGCGGTACGGGTGGTGGCGGCGGGTGACGCGCTGCTCGCCCCGTCCG
TGACCCGGCGCCTGATCGCGGACTTCGCCCGCCAACGGCCGTCCGGGGCTGGGCGCGGCGGGGCGGCGCTGCGGCTGAAC
GGGCTGACTCCACGCGAGACGGAGGTGCTGGAGCTGATAGCCCGGGGGCTGTCGAACCAGGAGATCGCGGGGCAGCTGGT
GCTGGCGGAACAGACGGTGAAGACGCACATCGGGCGGATACTCGCGAAGCTGGATCTGCGCGACCGGGCCCAGGCGGTGA
TCTTCGCCTACGAGGCGGGCGTGGTGGTACCGGGCGAGAGCCCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.732

98.246

0.39
  degU Bacillus subtilis subsp. subtilis str. 168

37.118

100

0.373