Detailed information NTG0651066

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L3X15_RS08025
• Genome accession: NZ_CP091423
• Coordinates: 1634685..1635734 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain LSM29
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1629685..1640734

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3X15_RS08005 (L3X15_08005)	nadE	1630091..1630915 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
L3X15_RS08010 (L3X15_08010)	-	1632211..1632738 (-)	528	WP_012027591.1	VanZ family protein	-
L3X15_RS08015 (L3X15_08015)	rlmN	1632735..1633847 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
L3X15_RS08020 (L3X15_08020)	-	1633856..1634497 (-)	642	WP_012027595.1	YutD family protein	-
L3X15_RS08025 (L3X15_08025)	sepM	1634685..1635734 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
L3X15_RS08030 (L3X15_08030)	coaD	1635721..1636209 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
L3X15_RS08035 (L3X15_08035)	rsmD	1636199..1636738 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L3X15_RS08040 (L3X15_08040)	-	1637046..1637768 (-)	723	WP_012027598.1	lipoprotein	-
L3X15_RS08045 (L3X15_08045)	-	1637825..1638211 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
L3X15_RS08050 (L3X15_08050)	-	1638211..1638429 (-)	219	WP_004194736.1	YqgQ family protein	-
L3X15_RS08055 (L3X15_08055)	-	1638737..1639339 (-)	603	WP_012027601.1	response regulator transcription factor	-
L3X15_RS08060 (L3X15_08060)	-	1639336..1640430 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=651066 L3X15_RS08025 WP_012775295.1 1634685..1635734(-) (sepM) [Streptococcus suis strain LSM29]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=651066 L3X15_RS08025 WP_012775295.1 1634685..1635734(-) (sepM) [Streptococcus suis strain LSM29]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605