Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA88_RS38635 Genome accession   NZ_CP107985
Coordinates   8575315..8575980 (+) Length   221 a.a.
NCBI ID   WP_328628937.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00353     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8570315..8580980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA88_RS38615 (OHA88_38675) - 8571095..8572309 (+) 1215 WP_326602019.1 geranylgeranyl reductase family protein -
  OHA88_RS38620 (OHA88_38680) - 8572492..8572941 (-) 450 WP_328628934.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHA88_RS38625 (OHA88_38685) - 8573072..8573803 (+) 732 WP_328628935.1 TetR/AcrR family transcriptional regulator -
  OHA88_RS38630 (OHA88_38690) - 8573933..8575318 (+) 1386 WP_328628936.1 sensor histidine kinase -
  OHA88_RS38635 (OHA88_38695) vraR 8575315..8575980 (+) 666 WP_328628937.1 response regulator transcription factor Regulator
  OHA88_RS38640 (OHA88_38700) - 8575941..8576255 (-) 315 WP_328628938.1 DUF6332 family protein -
  OHA88_RS38645 (OHA88_38705) - 8576360..8577874 (-) 1515 WP_267006755.1 MFS transporter -
  OHA88_RS38650 (OHA88_38710) - 8577962..8578363 (+) 402 WP_328628939.1 MarR family transcriptional regulator -
  OHA88_RS38655 (OHA88_38715) - 8578408..8579169 (-) 762 WP_328628940.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHA88_RS38660 (OHA88_38720) - 8579191..8579559 (-) 369 WP_328628941.1 hypothetical protein -
  OHA88_RS38665 (OHA88_38725) - 8579682..8580899 (-) 1218 WP_328628942.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23989.79 Da        Isoelectric Point: 4.7908

>NTDB_id=650884 OHA88_RS38635 WP_328628937.1 8575315..8575980(+) (vraR) [Streptomyces sp. NBC_00353]
MIRVLLADDQLLVRAGFRALLDAQPDIEVVGEAADGAEAVRLVRELRPDIVLMDIRMPHLDGLAATRTITGDPELNDVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVGGDALLSPGVTRRLIAEFAARSKEPAAATGLSELTERER
EVMALVGIGLTNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=650884 OHA88_RS38635 WP_328628937.1 8575315..8575980(+) (vraR) [Streptomyces sp. NBC_00353]
GTGATCCGCGTACTGCTCGCCGATGACCAGCTGTTGGTCCGGGCCGGTTTCCGCGCCCTGCTGGACGCGCAGCCGGACAT
CGAGGTGGTGGGGGAGGCTGCCGACGGTGCGGAGGCGGTACGTCTGGTGCGCGAACTGCGGCCGGACATCGTGCTGATGG
ACATCCGGATGCCGCATCTCGACGGCCTCGCCGCCACCCGCACGATCACCGGCGATCCGGAGCTCAACGACGTCAAGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCCGAGGAACTGCTGCGGGCGGTACGGGCCGTGGTGGGCGGCGACGCGCTGCTCTCGCCCGGAGTGACCCGAC
GGCTGATCGCCGAGTTCGCCGCCCGCTCCAAGGAGCCTGCGGCCGCGACGGGACTGAGCGAACTCACCGAACGGGAACGG
GAAGTGATGGCGCTGGTCGGCATCGGCCTCACCAACGAGGAGATCGCCCGCCGACTCGTCGTCAGCCCGCTCACCGCCAA
GACCCATGTCAGCCGCACCATGGTGAAGCTCGGCGCCCGCGACCGGGCCCAACTCGTCGTGCTCGCCTATGAGTCCGGGC
TCGTACGCCCCGGTTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.285

0.371
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.371