Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA88_RS26165 Genome accession   NZ_CP107985
Coordinates   5775411..5776088 (+) Length   225 a.a.
NCBI ID   WP_326604460.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00353     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5770411..5781088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA88_RS26145 (OHA88_26185) - 5770706..5771719 (+) 1014 WP_328627287.1 hypothetical protein -
  OHA88_RS26150 (OHA88_26190) - 5771773..5772915 (-) 1143 WP_328627288.1 NADH-quinone oxidoreductase subunit D -
  OHA88_RS26155 (OHA88_26195) - 5773041..5774072 (-) 1032 WP_328627289.1 SAM-dependent methyltransferase -
  OHA88_RS26160 (OHA88_26200) - 5774169..5775368 (+) 1200 WP_328627290.1 sensor histidine kinase -
  OHA88_RS26165 (OHA88_26205) vraR 5775411..5776088 (+) 678 WP_326604460.1 response regulator transcription factor Regulator
  OHA88_RS26170 (OHA88_26210) - 5776108..5777220 (-) 1113 WP_328629795.1 DUF5937 family protein -
  OHA88_RS26175 (OHA88_26215) - 5777325..5777585 (+) 261 WP_328627291.1 hypothetical protein -
  OHA88_RS26180 (OHA88_26220) - 5777622..5778857 (-) 1236 WP_328627292.1 beta-eliminating lyase-related protein -
  OHA88_RS26185 (OHA88_26225) - 5779039..5779998 (+) 960 WP_326629332.1 DUF2520 domain-containing protein -
  OHA88_RS26190 (OHA88_26230) panC 5779995..5781005 (+) 1011 WP_328627293.1 pantoate--beta-alanine ligase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24192.09 Da        Isoelectric Point: 6.2654

>NTDB_id=650855 OHA88_RS26165 WP_326604460.1 5775411..5776088(+) (vraR) [Streptomyces sp. NBC_00353]
MAIRVMLVDDQVLLRTGFRMVLAAQPDMEVVAEAGDGAEAIENLRSTAVDVVLMDVRMPRLDGVEATRRICARPDAPKVL
ILTTFDLDEYAFSGLKAGASGFMLKDVPPAELLGAIRSVHSGDAVVAPSTTRRLLDRFSSMLPSSTDEPKHKDIGKLTER
EREVMLLVAQGMSNGEIAARLVLSEATVKTHVGRILTKLNLRDRVQVVVLAYETGLVRAGGGGAG

Nucleotide


Download         Length: 678 bp        

>NTDB_id=650855 OHA88_RS26165 WP_326604460.1 5775411..5776088(+) (vraR) [Streptomyces sp. NBC_00353]
ATGGCGATCCGCGTGATGCTCGTCGACGACCAGGTACTGCTGCGCACCGGCTTCCGGATGGTGCTCGCGGCGCAGCCGGA
CATGGAGGTCGTCGCCGAGGCCGGCGACGGCGCAGAGGCGATCGAGAACCTTCGCTCCACCGCCGTCGACGTGGTGCTGA
TGGACGTGCGCATGCCGAGGCTGGACGGTGTCGAGGCGACCCGGCGCATCTGCGCCCGGCCCGATGCGCCCAAGGTGCTC
ATCCTGACCACGTTCGACCTGGACGAATACGCCTTCTCCGGTCTGAAGGCCGGGGCCAGCGGTTTCATGCTCAAGGACGT
GCCGCCGGCCGAACTGCTCGGCGCGATCCGTTCGGTGCACAGCGGCGACGCGGTCGTCGCCCCGTCCACCACCCGGCGGC
TGCTCGACCGCTTCTCGTCCATGCTGCCGAGCAGCACCGACGAACCCAAGCACAAGGACATCGGCAAGCTCACCGAACGC
GAACGCGAAGTGATGCTGCTGGTCGCGCAGGGCATGTCGAACGGCGAGATCGCGGCGCGGCTGGTGCTCTCCGAGGCGAC
GGTCAAGACGCACGTCGGCCGCATCCTCACCAAGCTGAACCTGCGCGACCGGGTGCAGGTCGTCGTGCTCGCGTACGAGA
CGGGGCTGGTGCGGGCCGGCGGAGGCGGGGCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.557

98.222

0.369
  degU Bacillus subtilis subsp. subtilis str. 168

37.22

99.111

0.369