Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA88_RS22950 Genome accession   NZ_CP107985
Coordinates   5083000..5083662 (-) Length   220 a.a.
NCBI ID   WP_328626879.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00353     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5078000..5088662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA88_RS22925 (OHA88_22960) - 5078010..5078282 (+) 273 WP_267003640.1 DUF1876 domain-containing protein -
  OHA88_RS22930 (OHA88_22965) - 5078328..5078861 (-) 534 WP_267003642.1 MarR family transcriptional regulator -
  OHA88_RS22935 (OHA88_22970) - 5078975..5079898 (+) 924 WP_328626876.1 ABC transporter ATP-binding protein -
  OHA88_RS22940 (OHA88_22975) - 5079895..5081496 (+) 1602 WP_328626877.1 ABC transporter permease -
  OHA88_RS22945 (OHA88_22980) - 5081733..5082962 (-) 1230 WP_328626878.1 cytochrome P450 -
  OHA88_RS22950 (OHA88_22985) vraR 5083000..5083662 (-) 663 WP_328626879.1 response regulator transcription factor Regulator
  OHA88_RS22955 (OHA88_22990) - 5083659..5084984 (-) 1326 WP_328626880.1 histidine kinase -
  OHA88_RS22960 (OHA88_22995) - 5085116..5085991 (-) 876 WP_326814762.1 alpha/beta hydrolase -
  OHA88_RS22965 (OHA88_23000) kynU 5086101..5087339 (-) 1239 WP_328626881.1 kynureninase -
  OHA88_RS22970 (OHA88_23005) - 5087332..5088180 (-) 849 WP_267003656.1 tryptophan 2,3-dioxygenase family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23525.31 Da        Isoelectric Point: 4.9350

>NTDB_id=650850 OHA88_RS22950 WP_328626879.1 5083000..5083662(-) (vraR) [Streptomyces sp. NBC_00353]
MNDIRVLIVDDQMMVREGFSVLLGAMPGIEVVGEAVDGRQAIAQAAALRPDVVLMDIRMPELNGIEATREIVANDAAAKV
LVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTKRLITEFSRLAGAPRTPALARIGDLTER
ETEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPA

Nucleotide


Download         Length: 663 bp        

>NTDB_id=650850 OHA88_RS22950 WP_328626879.1 5083000..5083662(-) (vraR) [Streptomyces sp. NBC_00353]
ATGAACGACATCCGTGTCCTGATCGTCGACGACCAGATGATGGTCCGTGAGGGCTTCTCGGTGCTCCTGGGGGCGATGCC
GGGCATCGAGGTCGTCGGCGAGGCCGTCGACGGCCGGCAGGCCATCGCCCAGGCCGCCGCGCTGCGGCCCGACGTGGTGC
TGATGGACATCCGGATGCCGGAGCTCAACGGCATCGAGGCGACCCGTGAGATCGTCGCGAACGACGCGGCCGCCAAGGTG
CTCGTGCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCCGGGTTTCTGCTGAAGGA
CGCCTCCGCCCGCCAGCTCGCCGACGGGGTACGGGTGGTGGCGGCCGGGGAGGCGCTGCTGGCACCGACCGTCACGAAGC
GGCTGATCACCGAGTTCTCCCGGCTCGCCGGGGCCCCGCGGACGCCCGCGCTCGCCCGGATCGGCGATCTGACGGAGCGC
GAGACGGAAGTGCTCGTCCTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCTCGCACCTGGTGGTCGCCGAGTCCAC
CATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGGCTGCGGGACCGTACGCAGGCGGCGGTGTTCGCGTACGAGG
CGCGGCTGGTCACCCCGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.393

97.273

0.432
  degU Bacillus subtilis subsp. subtilis str. 168

42.727

100

0.427