Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA88_RS22400 Genome accession   NZ_CP107985
Coordinates   4963891..4964517 (+) Length   208 a.a.
NCBI ID   WP_326628428.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00353     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4958891..4969517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA88_RS22380 (OHA88_22420) - 4959697..4961097 (-) 1401 WP_328626814.1 M1 family metallopeptidase -
  OHA88_RS22385 (OHA88_22425) - 4961145..4961747 (-) 603 WP_328626815.1 ankyrin repeat domain-containing protein -
  OHA88_RS22390 (OHA88_22430) - 4961780..4962337 (-) 558 WP_328626816.1 heme-binding protein -
  OHA88_RS22395 (OHA88_22435) - 4962590..4963894 (+) 1305 WP_328626817.1 sensor histidine kinase -
  OHA88_RS22400 (OHA88_22440) vraR 4963891..4964517 (+) 627 WP_326628428.1 response regulator transcription factor Regulator
  OHA88_RS22405 (OHA88_22445) - 4964640..4965137 (+) 498 WP_267003488.1 hypothetical protein -
  OHA88_RS22410 (OHA88_22450) - 4965165..4965866 (-) 702 WP_328626818.1 pentapeptide repeat-containing protein -
  OHA88_RS22415 (OHA88_22455) - 4965966..4967165 (+) 1200 WP_328626819.1 NAD(P)-binding protein -
  OHA88_RS22420 (OHA88_22460) - 4967212..4968213 (+) 1002 WP_328626820.1 zinc-binding dehydrogenase -
  OHA88_RS22425 (OHA88_22465) - 4968231..4968704 (-) 474 WP_267003496.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 22082.40 Da        Isoelectric Point: 5.1096

>NTDB_id=650847 OHA88_RS22400 WP_326628428.1 4963891..4964517(+) (vraR) [Streptomyces sp. NBC_00353]
MTPPAVRILLCDDHAVVRAGLLALLGSEPDIEVVGEAGSGEEAVALAARLTPDVVLMDLQLGEGIDGVEATRRIAVTGVH
VLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSPPVASRVMARMRSPLPTLTDRERDILGQLSQ
GLGNREIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 627 bp        

>NTDB_id=650847 OHA88_RS22400 WP_326628428.1 4963891..4964517(+) (vraR) [Streptomyces sp. NBC_00353]
ATGACCCCGCCCGCCGTACGGATCCTGCTCTGCGACGACCACGCCGTCGTACGCGCCGGACTGCTCGCCCTCCTGGGCAG
CGAACCGGACATCGAGGTCGTCGGCGAGGCGGGCAGCGGCGAGGAGGCCGTCGCCCTGGCCGCCCGGCTGACCCCCGACG
TCGTCCTGATGGACCTCCAACTGGGCGAAGGAATCGACGGCGTCGAAGCCACCCGCCGCATCGCGGTCACCGGCGTCCAT
GTCCTCGTCCTCACGACGTACGACACCGACGCCGACATCACCCGCGCCATCGAAGCGGGCGCCACCGGCTACCTGCTGAA
GGCGGAACGCCCGGAGGAACTGTTCGCCGCGATCCGCTCGGCGGCCCAGGGCCGCACCACGCTCTCCCCGCCGGTTGCCA
GCCGTGTCATGGCCCGCATGCGCAGCCCCCTGCCGACGCTCACGGACCGCGAACGCGACATCCTGGGCCAGCTGTCCCAG
GGCCTGGGCAACCGGGAGATCGCCCGGGCCCTGTTCATCAGCGAGGCCACGGTCAAGACGCACCTGGGCCGCATCTACGA
CAAACTCGGCGTCGACACCCGCGCAGGCGCCGTGTCCGTGGCGAAGGAGCAGCGGCTGCTGCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.097

99.519

0.399
  degU Bacillus subtilis subsp. subtilis str. 168

35.78

100

0.375