Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT74_RS31985 Genome accession   NZ_CP107983
Coordinates   6958778..6959428 (-) Length   216 a.a.
NCBI ID   WP_266669230.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00354     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6953778..6964428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT74_RS31970 (OHT74_32005) - 6955191..6956042 (-) 852 WP_266669224.1 alpha/beta fold hydrolase -
  OHT74_RS31975 (OHT74_32010) - 6956387..6957148 (+) 762 WP_266669226.1 GntR family transcriptional regulator -
  OHT74_RS31980 (OHT74_32015) - 6957503..6958660 (-) 1158 WP_267000784.1 ROK family transcriptional regulator -
  OHT74_RS31985 (OHT74_32020) vraR 6958778..6959428 (-) 651 WP_266669230.1 response regulator transcription factor Regulator
  OHT74_RS31990 (OHT74_32025) - 6959433..6960608 (-) 1176 WP_328622074.1 histidine kinase -
  OHT74_RS31995 (OHT74_32030) - 6960717..6961628 (+) 912 WP_328622075.1 ATP-binding cassette domain-containing protein -
  OHT74_RS32000 (OHT74_32035) - 6961655..6962404 (+) 750 WP_328622076.1 ABC transporter permease -
  OHT74_RS32005 (OHT74_32040) - 6962445..6962879 (+) 435 WP_266669236.1 hypothetical protein -
  OHT74_RS32010 (OHT74_32045) mug 6962876..6963418 (-) 543 WP_328623435.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23221.88 Da        Isoelectric Point: 4.9794

>NTDB_id=650796 OHT74_RS31985 WP_266669230.1 6958778..6959428(-) (vraR) [Streptomyces sp. NBC_00354]
MPVTVLLVDDEPLVRAGLRAVLDAQPDIEVVGEAADGASVVPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRTVDSPPKI
LVVTTFENDEYVYQALRAGADGFLLKRARPSEIVHAVRLVAEGETLLFPAAVRALAAEYGNRQARAVLERAALTEREEAV
LRLMARGLTNVEIARELIVGTETVKSHVSAILGKLGARDRTQAVIAAYESGFVAPA

Nucleotide


Download         Length: 651 bp        

>NTDB_id=650796 OHT74_RS31985 WP_266669230.1 6958778..6959428(-) (vraR) [Streptomyces sp. NBC_00354]
ATGCCGGTTACCGTTCTGCTCGTCGATGACGAACCTCTGGTGCGTGCGGGTCTGCGTGCCGTCCTGGATGCCCAGCCCGA
CATCGAAGTGGTGGGTGAGGCGGCCGACGGGGCCTCCGTCGTCCCGCTCGTCCGGCAGTTGAGGCCGGACGTGGTGGCGA
TGGACGTGCGGATGCCGCTGCTCGACGGGATCGAGGCGACCCGGGCGGTGCTGCGGACCGTGGACTCCCCGCCGAAGATC
CTCGTGGTGACCACCTTCGAGAACGACGAGTACGTGTACCAGGCCCTGCGGGCCGGAGCGGACGGGTTCCTGCTGAAGCG
GGCCCGCCCCTCCGAGATCGTGCACGCGGTACGGCTCGTGGCGGAGGGCGAGACGCTGCTCTTCCCCGCGGCCGTACGGG
CCCTCGCCGCGGAGTACGGGAACCGGCAGGCGCGGGCGGTGCTGGAGCGGGCCGCGCTGACCGAGCGGGAGGAGGCGGTG
CTGCGGCTGATGGCACGAGGGCTGACGAACGTCGAGATCGCCCGCGAGCTGATCGTCGGCACGGAGACGGTGAAGTCCCA
TGTGAGCGCAATTCTGGGCAAGCTGGGGGCACGAGACCGGACCCAGGCCGTGATCGCGGCGTACGAGTCGGGATTCGTCG
CCCCGGCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.654

99.074

0.403
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.366