Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT74_RS21700 Genome accession   NZ_CP107983
Coordinates   4744496..4745137 (-) Length   213 a.a.
NCBI ID   WP_328621104.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00354     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4739496..4750137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT74_RS21670 (OHT74_21700) - 4739761..4740240 (+) 480 WP_266666013.1 GNAT family N-acetyltransferase -
  OHT74_RS21675 (OHT74_21705) - 4740270..4740773 (-) 504 WP_266666014.1 FBP domain-containing protein -
  OHT74_RS21680 (OHT74_21710) - 4740842..4741834 (-) 993 WP_328623361.1 zinc-binding dehydrogenase -
  OHT74_RS21685 (OHT74_21715) - 4741950..4742624 (+) 675 WP_266666015.1 pentapeptide repeat-containing protein -
  OHT74_RS21690 (OHT74_21720) - 4742650..4743153 (-) 504 WP_266666016.1 hypothetical protein -
  OHT74_RS21695 (OHT74_21725) - 4743227..4744198 (-) 972 Protein_4282 M4 family metallopeptidase -
  OHT74_RS21700 (OHT74_21730) vraR 4744496..4745137 (-) 642 WP_328621104.1 response regulator transcription factor Regulator
  OHT74_RS21705 (OHT74_21735) - 4745134..4746261 (-) 1128 WP_266999470.1 sensor histidine kinase -
  OHT74_RS21710 (OHT74_21740) - 4746632..4747189 (+) 558 WP_266666017.1 heme-binding protein -
  OHT74_RS21715 (OHT74_21745) - 4747300..4748718 (+) 1419 WP_328621105.1 M1 family metallopeptidase -
  OHT74_RS21720 (OHT74_21750) - 4748826..4749401 (-) 576 WP_266995416.1 TerD family protein -
  OHT74_RS21725 (OHT74_21755) arfB 4749582..4750007 (+) 426 WP_030156996.1 alternative ribosome rescue aminoacyl-tRNA hydrolase ArfB -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22357.69 Da        Isoelectric Point: 5.3006

>NTDB_id=650769 OHT74_RS21700 WP_328621104.1 4744496..4745137(-) (vraR) [Streptomyces sp. NBC_00354]
MTTGTGPMTTILLCDDHAVVRAGLLALLGSAPDIEVVGEAGSGEEAVALAAMLRPDVVLMDLQLGEGIDGVEATRRITAV
TDPPHVLVLTTYDTDADVTRAIAAGATGYLLKAERPEELFSAIHSAAAGRTTLSPPVASRVMAHMRGSRPTLTDRELDIL
GQLARGLGNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLL

Nucleotide


Download         Length: 642 bp        

>NTDB_id=650769 OHT74_RS21700 WP_328621104.1 4744496..4745137(-) (vraR) [Streptomyces sp. NBC_00354]
ATGACGACTGGAACCGGCCCGATGACGACGATCCTCCTCTGCGACGACCACGCGGTGGTCCGCGCCGGCCTGCTGGCGCT
GCTGGGCAGCGCGCCGGACATCGAGGTCGTGGGCGAGGCCGGCAGCGGCGAGGAGGCGGTGGCCCTGGCGGCGATGCTCC
GCCCGGACGTGGTGCTGATGGACCTCCAGCTGGGCGAGGGCATCGACGGGGTCGAAGCCACCCGCCGCATCACGGCGGTG
ACCGACCCCCCGCACGTCCTGGTCCTCACGACGTACGACACGGACGCGGACGTCACCCGCGCCATCGCGGCGGGCGCCAC
GGGCTACCTGCTGAAGGCGGAGCGCCCGGAGGAGCTGTTCTCCGCGATCCACTCGGCGGCAGCGGGCCGTACGACGCTCT
CGCCGCCGGTGGCCAGCCGCGTGATGGCCCACATGCGGGGCTCGCGCCCGACGCTGACGGACCGCGAGCTAGACATCCTG
GGCCAGCTGGCGCGGGGGCTGGGCAACCGGGACATCGCCCGGGCCCTGTTCATCAGCGAGGCCACGGTGAAGACCCACCT
GGGCCGCATCTACGACAAGCTCGGCGTGGACACCCGCGCGGGAGCGGTCTCGGTGGCCAAGGAACAGCGCCTGCTGCTCT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(11-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40

96.244

0.385
  degU Bacillus subtilis subsp. subtilis str. 168

35.484

100

0.362