Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT74_RS04710 Genome accession   NZ_CP107983
Coordinates   987726..988406 (+) Length   226 a.a.
NCBI ID   WP_266660887.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00354     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 982726..993406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT74_RS04685 (OHT74_04695) - 983466..984386 (+) 921 WP_328619442.1 serine protease -
  OHT74_RS04690 (OHT74_04700) - 984340..984735 (-) 396 WP_328619443.1 hypothetical protein -
  OHT74_RS04695 (OHT74_04705) - 984801..985337 (-) 537 WP_328619444.1 HXXEE domain-containing protein -
  OHT74_RS04700 (OHT74_04710) - 985334..986281 (-) 948 WP_266660885.1 AEC family transporter -
  OHT74_RS04705 (OHT74_04715) - 986422..987729 (+) 1308 WP_328623257.1 histidine kinase -
  OHT74_RS04710 (OHT74_04720) vraR 987726..988406 (+) 681 WP_266660887.1 response regulator transcription factor Regulator
  OHT74_RS04715 (OHT74_04725) - 988551..989594 (+) 1044 WP_328619445.1 alpha/beta hydrolase -
  OHT74_RS04720 (OHT74_04730) - 989591..990802 (+) 1212 WP_328619446.1 acyltransferase -
  OHT74_RS04725 (OHT74_04735) - 990973..991383 (+) 411 WP_328619447.1 hypothetical protein -
  OHT74_RS04730 (OHT74_04740) - 991460..991882 (-) 423 WP_266660895.1 DUF350 domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24362.18 Da        Isoelectric Point: 5.3448

>NTDB_id=650729 OHT74_RS04710 WP_266660887.1 987726..988406(+) (vraR) [Streptomyces sp. NBC_00354]
MTIRVIIVDDQAMVRAGFAALLSAQADIDVVGEAPDGRQGVQVSRTVHPDVVLMDVRMPEMDGLTAARELLSPPPGVVHR
PKVLMLTTFDIDDYVYEALRAGASGFLLKDAPPADLIAAVRVVASGEALLAPSVTRRLIADFVQQRPAPRKDPALRLNGL
TPRETEVLELIARGLSNQEIAGHLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYEAGLVRPGDSD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=650729 OHT74_RS04710 WP_266660887.1 987726..988406(+) (vraR) [Streptomyces sp. NBC_00354]
TTGACCATCCGTGTGATCATCGTCGACGACCAGGCCATGGTACGGGCGGGGTTCGCCGCTTTGCTGTCGGCGCAGGCCGA
CATCGACGTGGTGGGCGAGGCCCCCGACGGGCGGCAGGGGGTACAGGTCTCCCGCACCGTGCATCCCGACGTGGTGCTGA
TGGACGTACGCATGCCGGAGATGGACGGGCTCACGGCCGCCCGGGAGCTGCTCAGCCCGCCGCCGGGGGTCGTCCACCGG
CCGAAAGTGCTGATGCTGACCACCTTCGACATCGACGACTACGTGTACGAGGCGCTGCGCGCGGGCGCCTCCGGGTTCCT
GCTGAAGGACGCGCCGCCGGCCGATCTGATCGCGGCGGTGCGGGTGGTCGCGTCGGGCGAGGCGCTGCTGGCGCCCTCGG
TGACGCGGCGGCTGATCGCGGACTTCGTCCAGCAGCGGCCGGCCCCGCGCAAGGACCCGGCGCTGCGGCTGAACGGGCTG
ACCCCGCGGGAGACCGAGGTACTGGAGCTCATCGCGCGCGGACTGTCGAACCAGGAGATCGCCGGGCACCTGGTGCTGGC
GGAGCAGACGGTGAAGACGCACATCGGGCGAGTGCTGGCCAAGCTGGACCTGCGGGACCGGGCGCAGGCCGTGATCTTCG
CGTACGAGGCGGGGCTGGTCCGGCCGGGCGACTCCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(160-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.629

97.788

0.407
  degU Bacillus subtilis subsp. subtilis str. 168

37.445

100

0.376