Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB28_RS39450 Genome accession   NZ_CP107981
Coordinates   8687410..8688075 (+) Length   221 a.a.
NCBI ID   WP_327669121.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00356     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8682410..8693075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB28_RS39430 (OHB28_39440) - 8683416..8684714 (+) 1299 WP_327664776.1 geranylgeranyl reductase family protein -
  OHB28_RS39435 (OHB28_39445) - 8684749..8685207 (-) 459 WP_328634381.1 nitroreductase/quinone reductase family protein -
  OHB28_RS39440 (OHB28_39450) - 8685356..8686081 (+) 726 WP_328634382.1 TetR/AcrR family transcriptional regulator -
  OHB28_RS39445 (OHB28_39455) - 8686160..8687413 (+) 1254 WP_328634383.1 sensor histidine kinase -
  OHB28_RS39450 (OHB28_39460) vraR 8687410..8688075 (+) 666 WP_327669121.1 response regulator transcription factor Regulator
  OHB28_RS39455 (OHB28_39465) - 8688097..8688846 (-) 750 WP_328634384.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHB28_RS39460 (OHB28_39470) - 8688918..8690120 (-) 1203 WP_328635615.1 MFS transporter -
  OHB28_RS39465 (OHB28_39475) - 8690257..8691036 (-) 780 WP_267071627.1 DeoR/GlpR family DNA-binding transcription regulator -
  OHB28_RS39470 (OHB28_39480) - 8691229..8692146 (+) 918 WP_328634385.1 SIS domain-containing protein -
  OHB28_RS39475 (OHB28_39485) - 8692181..8693032 (+) 852 WP_328634386.1 class II fructose-bisphosphate aldolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24063.83 Da        Isoelectric Point: 4.7261

>NTDB_id=650714 OHB28_RS39450 WP_327669121.1 8687410..8688075(+) (vraR) [Streptomyces sp. NBC_00356]
MIRVLLADDQSLVRAGFRALLDAQSDIEVAGEAADGEEAVRLVRELRPDVVLMDIRMPLLDGLAATRRIGADADLEAVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVHGDALLSPGVTRRLIAEFAARSKEPATVAPLDELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=650714 OHB28_RS39450 WP_327669121.1 8687410..8688075(+) (vraR) [Streptomyces sp. NBC_00356]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTCGTCCGCGCCGGGTTCCGGGCGCTGCTCGACGCGCAGAGCGACAT
CGAGGTCGCGGGCGAGGCGGCGGACGGCGAGGAAGCGGTGCGCCTGGTGCGCGAACTCCGTCCCGACGTCGTGCTCATGG
ACATCCGCATGCCGCTGCTCGACGGCCTCGCGGCGACCCGCCGGATCGGCGCGGACGCCGACCTGGAGGCGGTGAAGGTG
GTCATGCTCACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCCATCCGCTCCGGGGCCTCCGGGTTCCTCGTCAAGGA
CACCGAGCCGGAGGAACTGCTGCGCGCCGTAAGGGCAGTTGTCCATGGCGACGCGCTGCTCTCGCCGGGCGTCACCCGCC
GCCTGATCGCCGAGTTCGCGGCGCGCTCGAAGGAGCCGGCGACCGTCGCGCCGCTCGACGAACTGACGGAGCGGGAAAGG
GAGGTGATGGCGCTCGTCGGCATCGGCCTGTCCAACGAGGAGATCGCCCGCCGCCTCGTCGTCAGCCCACTCACCGCGAA
GACCCATGTGAGCCGCACGATGGTGAAGCTGGGCGCCCGCGACCGGGCCCAACTGGTCGTCCTGGCCTATGAGTCGGGGC
TCGTGCGGCCGGGGTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371