Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB28_RS34630 Genome accession   NZ_CP107981
Coordinates   7604583..7605224 (+) Length   213 a.a.
NCBI ID   WP_327664024.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00356     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7599583..7610224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB28_RS34610 (OHB28_34610) - 7600420..7601163 (-) 744 WP_327664020.1 transglycosylase SLT domain-containing protein -
  OHB28_RS34615 (OHB28_34615) - 7601483..7602565 (-) 1083 WP_328633873.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHB28_RS34620 (OHB28_34620) - 7602565..7603260 (-) 696 WP_328633874.1 SDR family oxidoreductase -
  OHB28_RS34625 (OHB28_34625) - 7603445..7604590 (+) 1146 WP_328633875.1 GAF domain-containing sensor histidine kinase -
  OHB28_RS34630 (OHB28_34630) vraR 7604583..7605224 (+) 642 WP_327664024.1 response regulator transcription factor Regulator
  OHB28_RS34635 (OHB28_34635) - 7605430..7605675 (+) 246 WP_266721145.1 chaplin -
  OHB28_RS34640 (OHB28_34640) - 7605899..7606138 (+) 240 WP_267070927.1 chaplin -
  OHB28_RS34645 (OHB28_34645) - 7606216..7606998 (-) 783 WP_327664025.1 hypothetical protein -
  OHB28_RS34650 (OHB28_34650) - 7607164..7607961 (+) 798 WP_266721148.1 ABC transporter ATP-binding protein -
  OHB28_RS34655 (OHB28_34655) - 7608030..7608464 (+) 435 WP_266721149.1 NfeD family protein -
  OHB28_RS34660 (OHB28_34660) - 7608601..7609560 (+) 960 WP_266721150.1 SPFH domain-containing protein -
  OHB28_RS34665 (OHB28_34665) - 7609633..7610139 (-) 507 WP_327669869.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22879.20 Da        Isoelectric Point: 5.3711

>NTDB_id=650706 OHB28_RS34630 WP_327664024.1 7604583..7605224(+) (vraR) [Streptomyces sp. NBC_00356]
MADPIKVLLVDDHQVVRRGLRTFLEVQGDIEVVGEAADGAEGVARTEELKPDVVLMDVKMPVMDGVDALRRLRELDNPAK
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLAQEETNSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=650706 OHB28_RS34630 WP_327664024.1 7604583..7605224(+) (vraR) [Streptomyces sp. NBC_00356]
GTGGCTGACCCGATCAAGGTACTGCTGGTCGACGATCACCAGGTCGTCCGCCGGGGCCTGCGCACCTTCCTGGAGGTGCA
GGGCGACATCGAGGTCGTCGGCGAGGCGGCGGACGGCGCCGAAGGAGTCGCCCGCACCGAGGAGTTGAAGCCCGACGTCG
TCCTGATGGACGTCAAGATGCCGGTGATGGACGGAGTCGACGCCCTGCGCCGGCTCCGCGAACTCGACAACCCCGCCAAG
GTGTTGATCGTCACCAGCTTCACCGAGCAGCGCACCGTCGTCCCCGCCCTGCGCGCGGGGGCAGCCGGCTACGTCTACAA
GGACGTGGACCCCGACGCCCTGGCCGGCGCCATCCGTTCCGTCCACGCGGGCCACATCCTGCTGCAACCCGAGGTCGCGG
GTGCCCTGTTGGCCCAGGAAGAGACCAACAGCGGGCAGGGGAGGGGCGGTTCCCTCACGGAGCGCGAGCGCGAGGTGCTC
GGCCTGATCGCCGACGGCCGCTCGAACCGGGAGATCGCCCGCGCCCTCGTCCTCTCCGAGAAAACGGTGAAGACCCATGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGTACCCAGGCCGCCCTGTGGGCCGTGCGCCACGGCGCCGCGGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

47.619

98.592

0.469
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

100

0.404