Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB28_RS31420 Genome accession   NZ_CP107981
Coordinates   6904792..6905469 (-) Length   225 a.a.
NCBI ID   WP_266720021.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00356     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6899792..6910469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB28_RS31395 (OHB28_31395) - 6900135..6900602 (-) 468 WP_328633576.1 GNAT family N-acetyltransferase -
  OHB28_RS31400 (OHB28_31400) - 6900715..6901188 (+) 474 WP_327663525.1 MerR family transcriptional regulator -
  OHB28_RS31405 (OHB28_31405) - 6901194..6902240 (+) 1047 WP_328633577.1 aldo/keto reductase -
  OHB28_RS31410 (OHB28_31410) - 6902282..6903511 (-) 1230 WP_328633578.1 acyltransferase -
  OHB28_RS31415 (OHB28_31415) - 6903508..6904638 (-) 1131 WP_328633579.1 alpha/beta hydrolase -
  OHB28_RS31420 (OHB28_31420) vraR 6904792..6905469 (-) 678 WP_266720021.1 response regulator transcription factor Regulator
  OHB28_RS31425 (OHB28_31425) - 6905485..6906861 (-) 1377 WP_328633580.1 sensor histidine kinase -
  OHB28_RS31430 (OHB28_31430) - 6906943..6907821 (-) 879 WP_328633581.1 DUF4429 domain-containing protein -
  OHB28_RS31435 (OHB28_31435) - 6907898..6909109 (-) 1212 WP_328633582.1 alpha/beta hydrolase -
  OHB28_RS31440 (OHB28_31440) - 6909227..6909868 (-) 642 WP_266720028.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24234.14 Da        Isoelectric Point: 6.4996

>NTDB_id=650698 OHB28_RS31420 WP_266720021.1 6904792..6905469(-) (vraR) [Streptomyces sp. NBC_00356]
MTIRVIIVDDQTMVRAGFAALLNAQSDIDVVGEAPDGKEGVQVSRSTHPDVVLMDVRMPEMDGLAATKELMDPPPGVVHR
PKVLMLTTFDVDDYVYAALRAGASGFLLKDAPPADLISAVRVIAAGEALLAPTVTKRLIADFAKTRPANRKSHDPLLKTL
TPRESEVLELIARGLSNQEIAQKLVLAEQTVKTHIGRVLAKLGLRDRAQAVIFAYESGLVEPGGR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=650698 OHB28_RS31420 WP_266720021.1 6904792..6905469(-) (vraR) [Streptomyces sp. NBC_00356]
ATGACCATTCGCGTGATCATCGTCGACGACCAGACCATGGTGCGGGCGGGTTTCGCCGCGCTGCTGAACGCACAGAGCGA
CATCGACGTCGTGGGAGAGGCCCCGGACGGCAAGGAAGGCGTCCAGGTGAGCCGCTCCACGCATCCCGATGTCGTCCTCA
TGGATGTCCGGATGCCCGAGATGGACGGGCTGGCCGCAACGAAGGAACTGATGGACCCGCCGCCCGGCGTGGTGCACCGG
CCGAAGGTCCTGATGCTCACCACGTTCGACGTCGACGACTATGTGTACGCCGCGCTGCGGGCGGGCGCGTCCGGGTTTCT
GCTCAAGGACGCGCCACCGGCCGATCTGATCTCCGCGGTGCGCGTGATCGCGGCCGGTGAGGCGCTGCTCGCTCCCACGG
TCACCAAGCGTCTCATCGCGGACTTCGCCAAGACCCGCCCCGCAAACCGCAAGAGCCACGATCCGCTGCTGAAGACCCTG
ACACCGCGTGAGTCCGAGGTTCTCGAGCTGATCGCGCGCGGGCTGTCCAATCAGGAGATCGCGCAGAAGCTGGTGCTGGC
CGAGCAGACGGTGAAGACCCATATCGGCCGTGTGCTGGCGAAGTTGGGGCTGCGCGACCGGGCGCAGGCCGTGATCTTCG
CGTATGAATCGGGTCTTGTAGAGCCCGGCGGACGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(159-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.694

98.667

0.431
  degU Bacillus subtilis subsp. subtilis str. 168

37.281

100

0.378