Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB28_RS22660 Genome accession   NZ_CP107981
Coordinates   4969312..4969959 (+) Length   215 a.a.
NCBI ID   WP_328632770.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00356     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4964312..4974959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB28_RS22640 (OHB28_22645) - 4965269..4966402 (-) 1134 WP_328632769.1 YncE family protein -
  OHB28_RS22645 (OHB28_22650) - 4966399..4967001 (-) 603 WP_327671153.1 ankyrin repeat domain-containing protein -
  OHB28_RS22650 (OHB28_22655) - 4967163..4967732 (-) 570 WP_327662208.1 heme-binding protein -
  OHB28_RS22655 (OHB28_22660) - 4968063..4969262 (+) 1200 WP_328635507.1 sensor histidine kinase -
  OHB28_RS22660 (OHB28_22665) vraR 4969312..4969959 (+) 648 WP_328632770.1 response regulator transcription factor Regulator
  OHB28_RS22665 (OHB28_22670) - 4970014..4970514 (+) 501 WP_266712566.1 hypothetical protein -
  OHB28_RS22670 (OHB28_22675) - 4970535..4971245 (-) 711 WP_328632771.1 pentapeptide repeat-containing protein -
  OHB28_RS22675 (OHB28_22680) - 4971456..4972670 (+) 1215 WP_328632772.1 NAD(P)-binding protein -
  OHB28_RS22680 (OHB28_22685) - 4972742..4973758 (+) 1017 WP_328632773.1 zinc-binding dehydrogenase -
  OHB28_RS22685 (OHB28_22690) - 4973774..4974268 (-) 495 WP_328632774.1 nuclear transport factor 2 family protein -
  OHB28_RS22690 (OHB28_22695) - 4974388..4974942 (+) 555 WP_328632775.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 22977.36 Da        Isoelectric Point: 5.8900

>NTDB_id=650673 OHB28_RS22660 WP_328632770.1 4969312..4969959(+) (vraR) [Streptomyces sp. NBC_00356]
MTHPIRILLCDDHVVVRAGLLALLDSAAGIEVVGEAGTGEEAIALAAKLRPDVVLMDLQLGEGMDGVETTRRLTTDPDDP
ATGHRPHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIHAAAEGRTALSAPVASRVMANMRKPRPTLTDRERD
ILAQLAHGLGNREIAKALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 648 bp        

>NTDB_id=650673 OHB28_RS22660 WP_328632770.1 4969312..4969959(+) (vraR) [Streptomyces sp. NBC_00356]
ATGACTCACCCCATCCGCATCCTCCTCTGTGACGACCACGTCGTCGTTCGTGCCGGGTTGTTGGCGTTGCTCGACAGTGC
GGCGGGGATCGAGGTCGTCGGGGAGGCCGGTACCGGGGAGGAGGCGATCGCGCTCGCCGCGAAGCTCCGGCCCGACGTCG
TCCTCATGGACCTGCAGCTGGGCGAGGGCATGGACGGCGTGGAGACGACCCGCCGCCTCACCACCGACCCGGACGACCCG
GCCACCGGGCACCGCCCCCACGTCCTCGTTCTGACCACGTACGACACCGACGCCGACATCACCCGCGCCATCGAGGCGGG
CGCGACGGGCTATCTGCTCAAGGCGGAGCGGCCCGAGGAGCTGTTCGCCGCGATCCACGCGGCCGCGGAGGGCCGCACCG
CGCTGTCCGCCCCGGTCGCCAGCCGCGTCATGGCCAATATGCGCAAGCCGCGGCCCACCCTCACCGACCGCGAGCGCGAC
ATCCTCGCCCAGCTGGCGCACGGCCTCGGCAACCGGGAGATCGCCAAGGCCCTGTTCATCAGCGAGGCCACGGTCAAGAC
CCACCTGGGCCGCATCTACGACAAGCTCGGCGTGGACACCCGGGCCGGCGCCGTCTCGGTCGCGAAGGAGCAGCGGCTAC
TGCCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(153-208)

Response regulator receiver domain (Response_reg)

(7-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

100

0.386
  degU Bacillus subtilis subsp. subtilis str. 168

34.667

100

0.363