Detailed information NTG0650586

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHT01_RS18200
• Genome accession: NZ_CP107976
• Coordinates: 4325351..4326475 (+)
• Length: 374 a.a.
• NCBI ID: WP_261704645.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00358
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4320351..4331475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHT01_RS18185 (OHT01_18170)	-	4320682..4321521 (+)	840	WP_328554192.1	hypothetical protein	-
OHT01_RS18190 (OHT01_18175)	-	4321665..4323461 (-)	1797	WP_328554193.1	hypothetical protein	-
OHT01_RS18195 (OHT01_18180)	radA	4323873..4325282 (+)	1410	WP_328554194.1	DNA repair protein RadA	Machinery gene
OHT01_RS18200 (OHT01_18185)	disA	4325351..4326475 (+)	1125	WP_261704645.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHT01_RS18205 (OHT01_18190)	-	4326650..4327489 (-)	840	WP_328554195.1	hypothetical protein	-
OHT01_RS18210 (OHT01_18195)	-	4327681..4328598 (+)	918	WP_328554196.1	A/G-specific adenine glycosylase	-
OHT01_RS18215 (OHT01_18200)	-	4328851..4329390 (+)	540	WP_328554197.1	SigE family RNA polymerase sigma factor	-
OHT01_RS18220 (OHT01_18205)	-	4329378..4330028 (+)	651	WP_328554198.1	hypothetical protein	-
OHT01_RS18225 (OHT01_18210)	cseB	4330048..4330755 (+)	708	WP_328554199.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40025.79 Da
• Isoelectric Point: 4.9234

>NTDB_id=650586 OHT01_RS18200 WP_261704645.1 4325351..4326475(+) (disA) [Streptomyces sp. NBC_00358]
MAANDRAAAPGKSGGSSGADGLMRAALSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGYPIVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLTLQLDELIA
GVEPDRELVVRDYVPEPTAKRSRTVDEALSELDALAHAELLELSTVAKALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=650586 OHT01_RS18200 WP_261704645.1 4325351..4326475(+) (disA) [Streptomyces sp. NBC_00358]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCGCACT
GAGCGCCGTGGCACCCGGCACGGCGCTGCGCGACGGGCTTGAACGGATCCTCCGCGGCAACACGGGCGGACTCATCGTGC
TCGGCTCCGACAAGACCGTCGAAGCGATGTGTACGGGCGGGTTCGTCCTGGATGTGGAGTTCACCGCGACCCGTCTGCGT
GAACTGTGCAAGCTCGACGGCGGCATCGTGCTCGACAAGGACATCACCAAGATCCTCCGGGCGGGCGTGCAACTGGTGCC
CGACCCGACCATCCCGACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCGGCTACCCCA
TCGTCTCGGTCTCCCAGTCGATGCGTCTGATCGCGCTGTACGTCGACGGTCAGCGCCGCGTCCTGGAGGACTCCGCCGCG
ATCCTCTCGCGCGCCAACCAGGCCCTCGCCACGCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTCGCGGGAACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTCTCCGCGGTCGCGCAGCGTCTGGAGATGGTGCGCCGCATCG
CCACCGAGATCGCCGAGTACGTCGTCGAACTGGGCACGGACGGACGCCTGCTGACCCTCCAGCTCGACGAGCTGATCGCC
GGCGTCGAGCCCGATCGCGAACTGGTCGTCCGGGACTACGTGCCCGAGCCGACCGCCAAGCGTTCCCGCACGGTCGACGA
GGCGCTGTCCGAGCTGGACGCGCTCGCCCACGCCGAGTTGCTCGAACTCTCCACGGTGGCAAAGGCGTTGGGCTACACCG
GCTCTCCCGAGGCGCTCGACTCCGCGGTGTCCCCGCGCGGTTTCCGGCTCCTCGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTCGTGGAGCACTTCGGCGGGCTCCAGAAGCTTCTCGCCGCGAGCGTGGACGACCTCCAGACCGTCGA
CGGCGTGGGCGAGGCGCGGGCGCGCAGTGTCCGCGAGGGGCTGTCCCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436