Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG996_RS35115 Genome accession   NZ_CP107971
Coordinates   7652813..7653454 (+) Length   213 a.a.
NCBI ID   WP_266511785.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00366     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7647813..7658454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG996_RS35095 (OG996_35105) - 7648599..7649372 (-) 774 WP_266511796.1 transglycosylase SLT domain-containing protein -
  OG996_RS35100 (OG996_35110) - 7649670..7650755 (-) 1086 WP_328550595.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG996_RS35105 (OG996_35115) - 7650752..7651450 (-) 699 WP_266511790.1 SDR family NAD(P)-dependent oxidoreductase -
  OG996_RS35110 (OG996_35120) - 7651675..7652820 (+) 1146 WP_266511788.1 GAF domain-containing sensor histidine kinase -
  OG996_RS35115 (OG996_35125) vraR 7652813..7653454 (+) 642 WP_266511785.1 response regulator transcription factor Regulator
  OG996_RS35120 (OG996_35130) chpE 7653627..7653869 (+) 243 WP_266511782.1 chaplin ChpE -
  OG996_RS35125 (OG996_35135) - 7654088..7654876 (-) 789 WP_328550596.1 hypothetical protein -
  OG996_RS35130 (OG996_35140) - 7655014..7655811 (+) 798 WP_266511776.1 ABC transporter ATP-binding protein -
  OG996_RS35135 (OG996_35145) - 7655905..7656336 (+) 432 WP_266585641.1 NfeD family protein -
  OG996_RS35140 (OG996_35150) - 7656468..7657424 (+) 957 WP_266511772.1 SPFH domain-containing protein -
  OG996_RS35145 (OG996_35155) - 7657499..7658005 (-) 507 WP_266585642.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22839.14 Da        Isoelectric Point: 5.3711

>NTDB_id=650537 OG996_RS35115 WP_266511785.1 7652813..7653454(+) (vraR) [Streptomyces sp. NBC_00366]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELKPDVVLMDVKMPGMDGVDALRKLRELANPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=650537 OG996_RS35115 WP_266511785.1 7652813..7653454(+) (vraR) [Streptomyces sp. NBC_00366]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTGGTCCGCCGCGGCCTGCGCACGTTCCTCGAAGTGCA
GGACGACATCGAGGTCGTGGGCGAGGCGGCCGACGGCGCCGAAGGAGTGGCGCGTGCCGAGGAGTTGAAGCCCGACGTCG
TCCTGATGGACGTCAAGATGCCCGGCATGGACGGCGTCGACGCGCTCCGCAAGCTCCGCGAGCTGGCGAACCCCGCACGC
GTACTGATCGTGACCAGCTTCACCGAACAGCGCACGGTGGTCCCGGCCCTGCGCGCGGGCGCCGCCGGTTACGTCTACAA
GGACGTCGACCCGGACGCGCTCGCCGGAGCCATCCGCTCGGTCCACGCCGGGCACATCCTGCTCCAACCCGAGGTGGCGG
GCGCCCTGTTGTCCCAGGAGGAGGCCAACTCGGGCCAGGGGAGAGGCGGTTCGCTCACCGAGCGGGAGCGCGAGGTGCTC
GGCCTGATAGCGGACGGCCGCTCGAACCGGGAGATCGCGCGGGCCCTCGTCCTGTCCGAGAAGACCGTGAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGCACCCAGGCGGCGCTGTGGGCCGTACGCCACGGCGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399