Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS57_RS37455 Genome accession   NZ_CP107968
Coordinates   8543415..8544071 (+) Length   218 a.a.
NCBI ID   WP_328584947.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00370     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8538415..8549071
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS57_RS37435 (OHS57_37440) - 8539964..8540236 (-) 273 WP_328584943.1 hypothetical protein -
  OHS57_RS37440 (OHS57_37445) - 8540284..8541129 (-) 846 WP_328584944.1 ABC transporter permease subunit -
  OHS57_RS37445 (OHS57_37450) - 8541126..8542034 (-) 909 WP_328584945.1 ABC transporter ATP-binding protein -
  OHS57_RS37450 (OHS57_37455) - 8542168..8543415 (+) 1248 WP_328584946.1 sensor histidine kinase -
  OHS57_RS37455 (OHS57_37460) vraR 8543415..8544071 (+) 657 WP_328584947.1 response regulator transcription factor Regulator
  OHS57_RS37460 (OHS57_37465) - 8544130..8544366 (-) 237 Protein_7403 integrase core domain-containing protein -
  OHS57_RS37465 (OHS57_37470) - 8544371..8544544 (-) 174 Protein_7404 IS30 family transposase -
  OHS57_RS37470 (OHS57_37475) - 8544590..8545030 (+) 441 WP_328584948.1 molybdopterin cofactor-binding domain-containing protein -
  OHS57_RS37475 (OHS57_37480) - 8545272..8546075 (-) 804 WP_328584949.1 SDR family NAD(P)-dependent oxidoreductase -
  OHS57_RS37480 (OHS57_37485) - 8546131..8546574 (+) 444 WP_328584950.1 helix-turn-helix domain-containing protein -
  OHS57_RS37485 (OHS57_37490) - 8547298..8547552 (+) 255 WP_328584951.1 hypothetical protein -
  OHS57_RS37490 (OHS57_37495) - 8547549..8548694 (+) 1146 WP_328584952.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23171.74 Da        Isoelectric Point: 4.3199

>NTDB_id=650467 OHS57_RS37455 WP_328584947.1 8543415..8544071(+) (vraR) [Streptomyces sp. NBC_00370]
MTIRVVLTDDQPLVRAALQMVITDTADIEVVGEAEDGAEAVRLTAELAPDVVVMDLRMPGMDGIEATGLITAGTGATRVV
VLTTFDDDDYVYGALHAGASGFLVKDMALDDILAAIRIVAAGDALIAPAVTRRLIKEFTRPVVSPPRWSELDGITARERE
VLTLVGRGLSNTEIAGELSISIATAKTYLTRLLAKLNARDRVQLVILAYEAGLVATSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=650467 OHS57_RS37455 WP_328584947.1 8543415..8544071(+) (vraR) [Streptomyces sp. NBC_00370]
ATGACCATCCGTGTCGTGCTCACCGACGACCAGCCCCTGGTCCGGGCCGCCCTGCAGATGGTCATAACCGACACCGCGGA
CATCGAGGTGGTGGGCGAGGCAGAAGACGGTGCGGAAGCGGTACGCCTGACGGCGGAACTTGCCCCCGACGTCGTCGTGA
TGGACCTGCGGATGCCCGGTATGGACGGCATCGAGGCCACCGGGCTGATCACGGCGGGCACCGGCGCCACACGTGTCGTC
GTCCTGACGACCTTCGACGACGACGACTACGTCTATGGGGCGCTGCACGCCGGCGCGTCCGGATTCCTCGTCAAGGACAT
GGCTCTGGACGACATCCTTGCCGCAATCCGGATCGTTGCCGCCGGGGACGCCCTGATCGCACCAGCCGTGACACGCCGGC
TGATCAAAGAGTTCACCCGACCCGTAGTGTCACCGCCGCGGTGGTCGGAGCTCGACGGCATCACCGCCCGGGAACGGGAG
GTGCTGACCCTCGTCGGCAGAGGCCTGTCCAATACGGAGATCGCAGGCGAGCTCTCCATCAGCATCGCCACCGCCAAGAC
CTACCTGACCCGCCTGCTCGCCAAGCTCAATGCCCGCGACCGGGTGCAGCTAGTGATCCTGGCCTATGAGGCGGGCCTGG
TGGCAACATCCCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.785

98.165

0.381
  degU Bacillus subtilis subsp. subtilis str. 168

35.874

100

0.367