Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS57_RS17805 Genome accession   NZ_CP107968
Coordinates   4000170..4000829 (-) Length   219 a.a.
NCBI ID   WP_078863558.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00370     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3995170..4005829
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS57_RS17780 (OHS57_17795) - 3995208..3996362 (+) 1155 WP_328582604.1 hypothetical protein -
  OHS57_RS17785 (OHS57_17800) - 3996280..3996798 (-) 519 WP_041987845.1 MarR family transcriptional regulator -
  OHS57_RS17790 (OHS57_17805) - 3996874..3997773 (+) 900 WP_328582605.1 ABC transporter ATP-binding protein -
  OHS57_RS17795 (OHS57_17810) - 3997770..3999401 (+) 1632 WP_328582606.1 ABC transporter permease -
  OHS57_RS17800 (OHS57_17815) - 3999465..4000040 (-) 576 WP_041987838.1 Uma2 family endonuclease -
  OHS57_RS17805 (OHS57_17820) vraR 4000170..4000829 (-) 660 WP_078863558.1 response regulator transcription factor Regulator
  OHS57_RS17810 (OHS57_17825) - 4000826..4002145 (-) 1320 WP_041987837.1 histidine kinase -
  OHS57_RS17815 (OHS57_17830) - 4002382..4003281 (-) 900 WP_328582607.1 NAD(P)H-binding protein -
  OHS57_RS17820 (OHS57_17835) - 4003344..4004228 (-) 885 WP_328582608.1 alpha/beta hydrolase -
  OHS57_RS17825 (OHS57_17840) - 4004339..4004833 (-) 495 WP_328582609.1 rhodanese-like domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23564.24 Da        Isoelectric Point: 4.7218

>NTDB_id=650417 OHS57_RS17805 WP_078863558.1 4000170..4000829(-) (vraR) [Streptomyces sp. NBC_00370]
MTIRVLIVDDQVMVREGFSVLLNAMPDIEVVGEAVNGREAVTQVAALHPDVVLMDIRMPELNGIDATREIVAADAAAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTRRLITEFSRLAETPRAPALARVGDLTERE
TEVLVLIAQGLSNAEIAEHLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=650417 OHS57_RS17805 WP_078863558.1 4000170..4000829(-) (vraR) [Streptomyces sp. NBC_00370]
GTGACGATCCGGGTGCTGATCGTCGACGACCAGGTGATGGTCCGCGAGGGTTTCTCCGTACTGCTGAACGCGATGCCGGA
CATCGAGGTGGTGGGCGAGGCGGTGAACGGCCGCGAGGCCGTCACCCAGGTCGCCGCGCTCCACCCCGACGTGGTGCTGA
TGGACATCCGCATGCCGGAACTGAACGGCATCGACGCGACCCGCGAGATCGTCGCGGCGGACGCGGCGGCGAAGGTGCTG
GTCCTGACCACGTTCGACCTGGACGAGTACGTCTACCAGGCGCTGCGCGCCGGCGCTTCCGGCTTCCTGCTGAAGGACGC
GTCGGCGCGGCAACTGGCCGACGGCGTACGGGTGGTGGCGTCCGGCGAGGCACTGCTCGCCCCCACGGTCACCCGCCGCC
TGATCACGGAGTTCTCCCGCCTGGCGGAAACACCCCGCGCCCCGGCGCTGGCCCGGGTCGGTGACCTGACGGAGCGCGAG
ACGGAGGTGCTGGTGCTGATCGCCCAGGGCCTGTCGAACGCGGAGATCGCGGAGCACCTGGTGGTGGCGGAGTCCACGAT
CAAGACGCATGTGAGCCGCGTCCTGGTGAAGCTCGGCCTGCGGGACCGCACGCAGGCGGCGGTGTTCGCGTACGAGGCGC
GGCTGGTGACGCCGGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.519

98.63

0.429
  degU Bacillus subtilis subsp. subtilis str. 168

43.318

99.087

0.429