Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS57_RS11770 Genome accession   NZ_CP107968
Coordinates   2679961..2680641 (+) Length   226 a.a.
NCBI ID   WP_041990136.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00370     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2674961..2685641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS57_RS11750 (OHS57_11770) - 2675103..2676710 (-) 1608 WP_041990148.1 MFS transporter -
  OHS57_RS11755 (OHS57_11775) - 2676840..2677517 (+) 678 WP_328581876.1 TetR family transcriptional regulator -
  OHS57_RS11760 (OHS57_11780) - 2677606..2678823 (+) 1218 WP_328581877.1 alpha/beta hydrolase -
  OHS57_RS11765 (OHS57_11785) - 2678887..2679795 (+) 909 WP_328581878.1 DUF4429 domain-containing protein -
  OHS57_RS11770 (OHS57_11790) vraR 2679961..2680641 (+) 681 WP_041990136.1 response regulator transcription factor Regulator
  OHS57_RS11775 (OHS57_11795) - 2680760..2681803 (+) 1044 WP_328581879.1 alpha/beta hydrolase -
  OHS57_RS11780 (OHS57_11800) - 2681846..2682862 (-) 1017 WP_328581880.1 aldo/keto reductase -
  OHS57_RS11785 (OHS57_11805) - 2682869..2683336 (-) 468 WP_041990128.1 MerR family transcriptional regulator -
  OHS57_RS11790 (OHS57_11810) - 2683423..2683890 (+) 468 WP_328581881.1 GNAT family N-acetyltransferase -
  OHS57_RS11795 (OHS57_11815) - 2683911..2684732 (+) 822 WP_328581882.1 serine hydrolase domain-containing protein -
  OHS57_RS11800 (OHS57_11820) - 2684762..2685415 (-) 654 WP_328585047.1 pirin family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24191.01 Da        Isoelectric Point: 5.1120

>NTDB_id=650403 OHS57_RS11770 WP_041990136.1 2679961..2680641(+) (vraR) [Streptomyces sp. NBC_00370]
MTIRVIIVDDQAMVRAGFAALLSAQADIDVVGEAPDGRRGIEVSRATHPDVVLMDVRMPELDGLAAARELLDPPAGVVHL
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGDALLAPSVTRRLIADFTQRRPVQRKDPALRLHGL
TPRETEVLELIARGLSNLEIAADLVVAEQTVKTHVGRVLAKLDLRDRAQAVVFAYESGLVTPGAAN

Nucleotide


Download         Length: 681 bp        

>NTDB_id=650403 OHS57_RS11770 WP_041990136.1 2679961..2680641(+) (vraR) [Streptomyces sp. NBC_00370]
TTGACCATTCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGCGCCGGTTTCGCCGCGCTGCTGTCGGCGCAGGCCGA
CATCGACGTGGTGGGCGAGGCGCCGGACGGCAGGCGCGGCATCGAGGTCAGCCGTGCCACCCACCCGGACGTGGTGCTGA
TGGACGTGCGGATGCCGGAGCTGGACGGACTCGCCGCCGCACGGGAGCTGTTGGACCCGCCGGCCGGGGTGGTCCATCTG
CCGAAGGTGCTGATGCTGACCACCTTCGACGTGGACGACTACGTCTACGAGGCGCTGCGCGCCGGCGCCTCGGGCTTTCT
GCTGAAGGACGCGCCGCCCGCCGATCTGATCGCCGCCGTACGGGTCGTGGCGGCCGGTGACGCGCTGCTCGCGCCGTCCG
TGACCCGGCGGCTGATCGCGGACTTCACCCAGCGGCGCCCCGTCCAGCGCAAGGACCCGGCCCTGCGGCTGCACGGCCTC
ACCCCGCGCGAGACCGAGGTGCTGGAGCTGATCGCCAGGGGGCTCTCCAACCTGGAGATCGCCGCCGATCTGGTGGTCGC
CGAGCAGACGGTGAAGACCCATGTCGGCCGGGTCCTGGCCAAGCTGGATCTGCGGGACCGCGCCCAGGCCGTCGTGTTCG
CCTACGAGTCGGGACTGGTCACCCCCGGCGCCGCGAACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-214)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.819

97.788

0.389
  degU Bacillus subtilis subsp. subtilis str. 168

37.991

100

0.385