Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS57_RS05705 Genome accession   NZ_CP107968
Coordinates   1306045..1306695 (+) Length   216 a.a.
NCBI ID   WP_328581229.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00370     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1301045..1311695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS57_RS05675 (OHS57_05690) mug 1301167..1301724 (+) 558 WP_041997916.1 G/U mismatch-specific DNA glycosylase -
  OHS57_RS05680 (OHS57_05695) - 1301787..1302332 (-) 546 WP_041997914.1 hypothetical protein -
  OHS57_RS05685 (OHS57_05700) - 1302553..1302990 (-) 438 WP_328581225.1 hypothetical protein -
  OHS57_RS05690 (OHS57_05705) - 1303031..1303777 (-) 747 WP_328581226.1 ABC transporter permease -
  OHS57_RS05695 (OHS57_05710) - 1303781..1304710 (-) 930 WP_328581227.1 ATP-binding cassette domain-containing protein -
  OHS57_RS05700 (OHS57_05715) - 1304819..1306048 (+) 1230 WP_328581228.1 histidine kinase -
  OHS57_RS05705 (OHS57_05720) vraR 1306045..1306695 (+) 651 WP_328581229.1 response regulator transcription factor Regulator
  OHS57_RS05710 (OHS57_05725) - 1306742..1307182 (-) 441 WP_041997904.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHS57_RS05715 (OHS57_05730) - 1307300..1308457 (+) 1158 WP_041997902.1 ROK family transcriptional regulator -
  OHS57_RS05720 (OHS57_05735) - 1308550..1309314 (-) 765 WP_041997899.1 GntR family transcriptional regulator -
  OHS57_RS05725 (OHS57_05740) - 1309387..1310343 (-) 957 WP_328581230.1 DMT family transporter -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22841.50 Da        Isoelectric Point: 6.4965

>NTDB_id=650392 OHS57_RS05705 WP_328581229.1 1306045..1306695(+) (vraR) [Streptomyces sp. NBC_00370]
MTVTVLLVDDEPLVRAGLRAVLEAQPDITVVGEAADGAAVIPLVRSLRPDVVAMDVRMPLMDGIEATRAVLRTVSPPPKI
LVVTTFENDEYVYRALRAGADGFLLKRARPAEIVHAVRLIAEGDSLLFPAAVRSLAAEYGNAEARRGLAAAGLTGREADV
LRLMAQGLTNAEIAGRLVVGAETVKSHVSAVLAKLGARDRTQAVITAYESGFVAPR

Nucleotide


Download         Length: 651 bp        

>NTDB_id=650392 OHS57_RS05705 WP_328581229.1 1306045..1306695(+) (vraR) [Streptomyces sp. NBC_00370]
ATGACGGTGACCGTGCTGCTGGTGGACGACGAGCCGCTGGTCCGCGCGGGGCTGCGGGCCGTGCTGGAGGCGCAGCCCGA
CATCACCGTGGTCGGCGAGGCGGCGGACGGCGCCGCCGTGATCCCGCTGGTGCGCTCCTTGCGTCCCGATGTGGTGGCGA
TGGACGTGCGGATGCCGTTGATGGACGGGATCGAGGCGACCAGGGCGGTCCTGCGGACGGTGTCGCCGCCGCCGAAGATC
CTGGTCGTCACGACCTTCGAGAACGACGAGTACGTCTACCGGGCGCTGCGGGCGGGCGCCGACGGCTTTCTGCTCAAGCG
CGCCCGCCCGGCCGAGATCGTGCATGCCGTTCGGCTGATCGCGGAGGGCGACTCGCTGCTGTTCCCCGCCGCTGTGCGCT
CACTCGCCGCGGAGTACGGCAACGCCGAGGCGCGCAGGGGGCTGGCCGCCGCCGGGCTGACCGGCCGTGAGGCGGACGTG
CTGCGGCTGATGGCCCAGGGGCTGACGAACGCGGAGATCGCCGGGCGGCTGGTGGTGGGCGCGGAGACGGTGAAGTCCCA
TGTGAGCGCGGTCCTCGCGAAGTTGGGGGCGCGGGACCGCACCCAGGCGGTCATCACGGCGTACGAGTCGGGGTTCGTCG
CGCCGCGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(153-207)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.845

98.611

0.403
  degU Bacillus subtilis subsp. subtilis str. 168

34.764

100

0.375