Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT17_RS40100 Genome accession   NZ_CP107967
Coordinates   8732628..8733278 (-) Length   216 a.a.
NCBI ID   WP_326714152.1    Uniprot ID   A0ABV4SPB0
Organism   Streptomyces sp. NBC_00371     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8727628..8738278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT17_RS40080 (OHT17_40100) - 8728341..8729171 (-) 831 WP_328542877.1 alpha/beta fold hydrolase -
  OHT17_RS40085 (OHT17_40105) - 8729355..8730233 (+) 879 WP_326714150.1 RNA polymerase sigma-70 factor -
  OHT17_RS40090 (OHT17_40110) - 8730493..8731260 (+) 768 WP_227293472.1 GntR family transcriptional regulator -
  OHT17_RS40095 (OHT17_40115) - 8731351..8732508 (-) 1158 WP_328542878.1 ROK family transcriptional regulator -
  OHT17_RS40100 (OHT17_40120) vraR 8732628..8733278 (-) 651 WP_326714152.1 response regulator transcription factor Regulator
  OHT17_RS40105 (OHT17_40125) - 8733324..8734565 (-) 1242 WP_328542879.1 histidine kinase -
  OHT17_RS40110 (OHT17_40130) - 8734674..8735603 (+) 930 WP_326714154.1 ATP-binding cassette domain-containing protein -
  OHT17_RS40115 (OHT17_40135) - 8735606..8736343 (+) 738 WP_328542880.1 ABC transporter permease -
  OHT17_RS40120 (OHT17_40140) - 8736407..8736841 (+) 435 WP_326714156.1 hypothetical protein -
  OHT17_RS40125 (OHT17_40145) - 8736932..8737747 (+) 816 WP_328542881.1 SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23066.65 Da        Isoelectric Point: 4.9654

>NTDB_id=650368 OHT17_RS40100 WP_326714152.1 8732628..8733278(-) (vraR) [Streptomyces sp. NBC_00371]
MPLTVLLVDDEPLVRAGLRAVLSAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRSVSEPPKI
LVITTFENDEYVYGALRAGADGFLLKRSRPAEIVNAVRLVAEGDSLLFPAAVRRLAAEYGNTSAREAMDRAALTEREAEV
LRLMTRGLSNAEIAVRLVVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVSPG

Nucleotide


Download         Length: 651 bp        

>NTDB_id=650368 OHT17_RS40100 WP_326714152.1 8732628..8733278(-) (vraR) [Streptomyces sp. NBC_00371]
ATGCCGCTCACCGTGCTTCTTGTCGACGATGAACCGCTGGTCCGCGCGGGGTTGCGTGCCGTGCTCTCGGCGCAGCCGGA
CATCGAGGTGGTGGGCGAGGCGGCCGACGGCGCCGCGGTGATCCCGCTCGTCCGACAGCTGCGTCCGGATGTGGTCGCCA
TGGATGTGCGCATGCCTCTCCTGGACGGGATCGAGGCCACGCGCGCGGTGCTGCGCAGTGTGTCCGAGCCGCCCAAGATC
CTGGTCATCACGACGTTCGAGAACGACGAGTACGTGTACGGGGCGCTGCGGGCGGGCGCCGACGGGTTCCTGCTGAAGCG
GTCGCGGCCCGCCGAGATCGTGAACGCGGTCCGGCTCGTGGCCGAGGGCGATTCCCTGCTGTTCCCCGCGGCCGTGCGGA
GGCTCGCGGCCGAGTACGGCAACACGTCGGCACGCGAGGCGATGGACCGCGCCGCGCTCACGGAGCGGGAGGCGGAGGTG
CTGCGCCTGATGACGCGGGGCCTGTCCAACGCGGAGATCGCCGTGCGGCTCGTCGTCGGCACGGAGACGGTCAAGTCGCA
TGTGAGCGCCGTCCTCGCCAAGCTCGGGGCACGGGACCGGACACAGGCCGTCATCGCCGCGTACGAGTCCGGTTTCGTGT
CGCCCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.654

99.074

0.403
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.375