Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT17_RS37050 Genome accession   NZ_CP107967
Coordinates   8078601..8079245 (+) Length   214 a.a.
NCBI ID   WP_266565853.1    Uniprot ID   A0ABV4SZ16
Organism   Streptomyces sp. NBC_00371     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8073601..8084245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT17_RS37030 (OHT17_37050) - 8074453..8075184 (-) 732 WP_326713700.1 transglycosylase SLT domain-containing protein -
  OHT17_RS37035 (OHT17_37055) - 8075480..8076562 (-) 1083 WP_327577225.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHT17_RS37040 (OHT17_37060) - 8076559..8077260 (-) 702 WP_327577224.1 SDR family oxidoreductase -
  OHT17_RS37045 (OHT17_37065) - 8077463..8078608 (+) 1146 WP_327577223.1 GAF domain-containing sensor histidine kinase -
  OHT17_RS37050 (OHT17_37070) vraR 8078601..8079245 (+) 645 WP_266565853.1 response regulator transcription factor Regulator
  OHT17_RS37055 (OHT17_37075) - 8079445..8079687 (+) 243 WP_100592533.1 chaplin -
  OHT17_RS37060 (OHT17_37080) - 8079887..8080126 (+) 240 WP_326713704.1 chaplin -
  OHT17_RS37065 (OHT17_37085) - 8080244..8081032 (-) 789 WP_327577222.1 hypothetical protein -
  OHT17_RS37070 (OHT17_37090) - 8081157..8081954 (+) 798 WP_327577221.1 ABC transporter ATP-binding protein -
  OHT17_RS37075 (OHT17_37095) - 8082019..8082450 (+) 432 WP_326713706.1 NfeD family protein -
  OHT17_RS37080 (OHT17_37100) - 8082591..8083523 (+) 933 WP_100592537.1 SPFH domain-containing protein -
  OHT17_RS37085 (OHT17_37105) - 8083596..8084102 (-) 507 WP_326713707.1 HNH endonuclease -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23181.46 Da        Isoelectric Point: 5.6857

>NTDB_id=650360 OHT17_RS37050 WP_266565853.1 8078601..8079245(+) (vraR) [Streptomyces sp. NBC_00371]
MADNRIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVARTEELRPDVVLMDVKMPVMDGVEALRKLRELANPA
RVLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHVLLQPEVAGALLSQEETNGGQGRGNSLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAAG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=650360 OHT17_RS37050 WP_266565853.1 8078601..8079245(+) (vraR) [Streptomyces sp. NBC_00371]
GTGGCTGACAACAGGATCCGGGTGCTGCTGGTCGACGACCACCAGGTCGTCCGTCGAGGGCTGCGCACGTTCCTCGAGGT
CCAGGACGACATCGAGGTCGTGGGGGAGGCGTCGGACGGCGCCGAGGGCGTCGCCCGTACCGAGGAGCTGAGGCCGGACG
TCGTCCTGATGGACGTCAAGATGCCCGTCATGGACGGCGTCGAGGCCCTGCGCAAGCTGCGCGAGCTGGCCAACCCCGCG
CGCGTGCTCATCGTCACGAGCTTCACCGAACAGCGCACCGTGGTCCCCGCCCTGCGCGCGGGCGCCGCCGGGTACGTCTA
CAAGGACGTCGACCCGGACGCCCTGGCCGGCGCCATCCGCTCGGTGCACGCGGGCCATGTGCTGCTCCAGCCGGAGGTCG
CCGGCGCCCTGCTCTCGCAGGAGGAGACCAACGGCGGGCAGGGGAGAGGCAATTCCCTGACCGAGCGGGAGCGCGAGGTG
CTCGGCCTGATCGCGGACGGCCGGTCGAACCGGGAGATCGCCCGCGCCCTCGTCCTCTCCGAGAAGACGGTCAAGACCCA
TGTGTCCAACATCCTGATGAAGCTCGACCTGGCGGACCGCACCCAGGCCGCTCTGTGGGCCGTACGCCATGGGGCGGCCG
GCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.455

97.664

0.444
  degU Bacillus subtilis subsp. subtilis str. 168

39.189

100

0.407