Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT17_RS33685 Genome accession   NZ_CP107967
Coordinates   7352519..7353196 (-) Length   225 a.a.
NCBI ID   WP_116502281.1    Uniprot ID   A0ABV4SJY5
Organism   Streptomyces sp. NBC_00371     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7347519..7358196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT17_RS33665 (OHT17_33690) - 7348405..7348866 (+) 462 WP_327577531.1 MerR family transcriptional regulator -
  OHT17_RS33670 (OHT17_33695) - 7348872..7349918 (+) 1047 WP_327577530.1 aldo/keto reductase -
  OHT17_RS33675 (OHT17_33700) - 7349988..7351205 (-) 1218 WP_327577529.1 acyltransferase -
  OHT17_RS33680 (OHT17_33705) - 7351202..7352332 (-) 1131 WP_327577528.1 alpha/beta hydrolase -
  OHT17_RS33685 (OHT17_33710) vraR 7352519..7353196 (-) 678 WP_116502281.1 response regulator transcription factor Regulator
  OHT17_RS33690 (OHT17_33715) - 7353213..7354577 (-) 1365 WP_328542659.1 sensor histidine kinase -
  OHT17_RS33695 (OHT17_33720) - 7354765..7355631 (-) 867 WP_326716106.1 DUF4429 domain-containing protein -
  OHT17_RS33700 (OHT17_33725) - 7355699..7356907 (-) 1209 WP_326713181.1 alpha/beta hydrolase -
  OHT17_RS33705 (OHT17_33730) - 7357068..7357712 (-) 645 WP_326713182.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24317.10 Da        Isoelectric Point: 4.9741

>NTDB_id=650354 OHT17_RS33685 WP_116502281.1 7352519..7353196(-) (vraR) [Streptomyces sp. NBC_00371]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGKQGVEVSRTTHPDVVLMDVRMPEMDGIAATRALLDPPPGVIHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGEALLAPTVTRRLIEDIARQRPSGRRDRSPELNCL
TPRETEVLELIARGLSNQEIAEKLVLAEQTVKTHIGRVLAKLGLRDRAQAVIFAYETGLVTPGDQ

Nucleotide


Download         Length: 678 bp        

>NTDB_id=650354 OHT17_RS33685 WP_116502281.1 7352519..7353196(-) (vraR) [Streptomyces sp. NBC_00371]
ATGACCATCCGCGTGATCATTGTCGACGACCAGGCCATGGTGCGAGCGGGGTTCGCCGCGCTGCTGGCCGCGCAGAGCGA
CATCGACGTCGTGGGCGAGGCTCCGGACGGCAAGCAGGGTGTCGAGGTCAGCCGGACGACACATCCCGATGTCGTCCTCA
TGGACGTGCGGATGCCCGAGATGGACGGGATCGCCGCGACCCGCGCGCTCCTCGACCCTCCACCGGGCGTGATCCACCGC
CCCAAGGTCCTGATGCTCACCACGTTCGACGTGGACGACTACGTGTACGAGGCCCTGCGCGCCGGCGCTTCGGGTTTCCT
CCTCAAGGACGCCCCGCCGGCCGATCTCATCGCGGCGGTGCGTGTGGTGGCCGCCGGAGAGGCGCTGCTCGCCCCGACGG
TCACACGCCGGCTCATCGAGGACATCGCGAGGCAGCGCCCGTCCGGCCGCAGGGACCGTTCGCCGGAGCTGAACTGCCTG
ACACCACGCGAGACCGAGGTCCTCGAACTCATCGCCCGGGGCCTGTCCAACCAGGAGATCGCGGAGAAGCTGGTGCTCGC
GGAGCAGACCGTGAAGACCCATATCGGCCGCGTGCTCGCGAAGTTGGGGCTGCGAGACCGGGCGCAGGCCGTGATTTTCG
CCTACGAGACCGGTCTCGTCACGCCCGGCGACCAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(159-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.273

97.778

0.413
  degU Bacillus subtilis subsp. subtilis str. 168

38.326

100

0.387