Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT17_RS05165 Genome accession   NZ_CP107967
Coordinates   1030294..1030962 (-) Length   222 a.a.
NCBI ID   WP_326708471.1    Uniprot ID   A0ABV4SV17
Organism   Streptomyces sp. NBC_00371     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1025294..1035962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT17_RS05140 (OHT17_05145) - 1025803..1026357 (+) 555 WP_328541593.1 hypothetical protein -
  OHT17_RS05145 (OHT17_05150) - 1026362..1027648 (+) 1287 WP_328541594.1 transporter -
  OHT17_RS05150 (OHT17_05155) - 1027685..1028689 (+) 1005 WP_328541595.1 twin-arginine translocation signal domain-containing protein -
  OHT17_RS05155 (OHT17_05160) - 1028733..1029704 (-) 972 WP_326708470.1 SDR family NAD(P)-dependent oxidoreductase -
  OHT17_RS05160 (OHT17_05165) - 1029904..1030089 (+) 186 Protein_1031 deaminase -
  OHT17_RS05165 (OHT17_05170) vraR 1030294..1030962 (-) 669 WP_326708471.1 response regulator transcription factor Regulator
  OHT17_RS05170 (OHT17_05175) - 1030959..1032242 (-) 1284 WP_326715783.1 sensor histidine kinase -
  OHT17_RS05175 (OHT17_05180) - 1032313..1033164 (-) 852 WP_328541596.1 ABC transporter permease -
  OHT17_RS05180 (OHT17_05185) - 1033161..1034099 (-) 939 WP_328541597.1 ATP-binding cassette domain-containing protein -
  OHT17_RS05185 (OHT17_05190) - 1034285..1035319 (-) 1035 WP_326708474.1 sodium-dependent transporter -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24079.67 Da        Isoelectric Point: 6.6547

>NTDB_id=650295 OHT17_RS05165 WP_326708471.1 1030294..1030962(-) (vraR) [Streptomyces sp. NBC_00371]
MTTVLVVDDQPLQRYGLRMLLDSVPETEVVGEAAHGADAVRKAAGLRPDVVLMDVRMPGMDGIEATRRIVATGDRSRVLV
MTTFDLDEYVYAALRAGASGFLLKDARPEELLAGIRAVAVGDAVIAPALTRRLLYEFARLVPPHANGSDEEPRLSSLTDR
EREILVAIGKGWTNGEIATRFVLSESTVKTHVGRVLSKIGARDRIQAVIFAYDHGLARPHGG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=650295 OHT17_RS05165 WP_326708471.1 1030294..1030962(-) (vraR) [Streptomyces sp. NBC_00371]
ATGACCACCGTGCTCGTCGTGGACGACCAGCCTCTCCAGCGGTACGGGCTGCGCATGCTCCTCGACTCCGTGCCCGAGAC
AGAGGTGGTCGGCGAGGCCGCGCACGGAGCCGACGCCGTGCGCAAGGCCGCCGGACTCCGCCCCGACGTCGTCCTCATGG
ACGTACGCATGCCGGGCATGGACGGCATCGAGGCCACGCGCCGCATCGTCGCCACGGGCGACCGCTCCCGCGTCCTCGTC
ATGACCACCTTCGACCTCGACGAGTACGTCTACGCGGCTCTGCGCGCCGGAGCCAGCGGCTTCCTCCTCAAGGACGCCCG
CCCCGAGGAACTCCTGGCCGGCATCCGTGCCGTGGCCGTCGGGGACGCGGTGATCGCACCGGCACTCACCCGCCGCCTGC
TGTACGAGTTCGCCCGACTCGTGCCACCCCACGCGAACGGGTCTGACGAGGAGCCGAGGCTGAGTTCCCTCACCGACCGC
GAACGCGAGATCCTCGTCGCCATCGGCAAGGGCTGGACCAACGGCGAGATCGCCACCCGCTTCGTCCTGTCGGAGTCCAC
GGTCAAGACCCATGTCGGCCGCGTCCTGTCCAAGATCGGCGCCCGCGACCGCATCCAGGCGGTGATCTTCGCCTACGACC
ACGGCCTGGCCCGGCCCCATGGGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-211)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

96.847

0.374
  degU Bacillus subtilis subsp. subtilis str. 168

36.364

99.099

0.36