Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG842_RS35350 Genome accession   NZ_CP107960
Coordinates   7875957..7876622 (+) Length   221 a.a.
NCBI ID   WP_266735020.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00376     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7870957..7881622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG842_RS35330 (OG842_35320) - 7872001..7873215 (+) 1215 WP_266735027.1 geranylgeranyl reductase family protein -
  OG842_RS35335 (OG842_35325) - 7873315..7873767 (-) 453 WP_266735025.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OG842_RS35340 (OG842_35330) - 7873896..7874603 (+) 708 WP_266735023.1 TetR/AcrR family transcriptional regulator -
  OG842_RS35345 (OG842_35335) - 7874698..7875960 (+) 1263 WP_266735021.1 sensor histidine kinase -
  OG842_RS35350 (OG842_35340) vraR 7875957..7876622 (+) 666 WP_266735020.1 response regulator transcription factor Regulator
  OG842_RS35355 (OG842_35345) - 7876722..7878227 (-) 1506 WP_266735019.1 MFS transporter -
  OG842_RS35360 (OG842_35350) - 7878315..7878716 (+) 402 WP_266735018.1 MarR family transcriptional regulator -
  OG842_RS35365 (OG842_35355) - 7878828..7879625 (-) 798 WP_266735016.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG842_RS35370 (OG842_35360) - 7879669..7880892 (-) 1224 WP_266735014.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23836.53 Da        Isoelectric Point: 4.7853

>NTDB_id=650283 OG842_RS35350 WP_266735020.1 7875957..7876622(+) (vraR) [Streptomyces sp. NBC_00376]
MIRVLLADDQSLVRAGFRALLDAQPEIEVAGEAADGAEAVRLVGELRPDIVLMDIRMPHLDGLAATRAITGDARLDDVRV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPDELLRAVRAVVGGDALLSPGVTRRLIAEFAARSKEPAVSTGLGELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=650283 OG842_RS35350 WP_266735020.1 7875957..7876622(+) (vraR) [Streptomyces sp. NBC_00376]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTGGTCCGGGCGGGCTTCCGGGCCCTGCTCGACGCCCAGCCCGAAAT
CGAGGTGGCCGGGGAGGCCGCCGACGGTGCGGAAGCCGTGCGCCTGGTGGGCGAACTGCGGCCCGACATCGTGCTGATGG
ACATCCGGATGCCGCATCTGGACGGCCTCGCCGCGACCCGCGCCATCACCGGGGACGCCCGGCTGGACGACGTCCGGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGGTCCGGGGCCTCCGGCTTCCTCGTCAAGGA
CACCGAACCGGACGAACTGCTGCGCGCCGTACGGGCGGTGGTGGGCGGCGACGCGCTGCTCTCGCCGGGGGTCACCCGGC
GCCTGATCGCCGAGTTCGCGGCCCGTTCCAAGGAACCCGCGGTATCGACCGGGCTGGGCGAACTCACCGAACGGGAGCGG
GAGGTGATGGCGCTCGTCGGGATAGGGCTCTCCAACGAGGAGATCGCCCGGCGCCTCGTCGTCAGCCCCCTCACCGCCAA
GACCCACGTCAGCCGCACCATGGTGAAGCTGGGCGCCCGCGACCGGGCCCAGCTCGTCGTGCTCGCCTACGAGTCGGGGC
TGGTGCGGCCGGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.5

97.738

0.367
  degU Bacillus subtilis subsp. subtilis str. 168

35.556

100

0.362