Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG842_RS26965 Genome accession   NZ_CP107960
Coordinates   6000009..6000692 (-) Length   227 a.a.
NCBI ID   WP_266733249.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00376     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5995009..6005692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG842_RS26940 (OG842_26930) - 5995562..5996167 (-) 606 WP_266733245.1 TetR/AcrR family transcriptional regulator -
  OG842_RS26945 (OG842_26935) - 5996264..5997109 (+) 846 WP_266733246.1 NAD(P)H-binding protein -
  OG842_RS26950 (OG842_26940) - 5997302..5997763 (+) 462 WP_266733842.1 MerR family transcriptional regulator -
  OG842_RS26955 (OG842_26945) - 5997763..5998779 (+) 1017 WP_266733247.1 aldo/keto reductase -
  OG842_RS26960 (OG842_26950) - 5998796..5999842 (-) 1047 WP_266733248.1 alpha/beta hydrolase -
  OG842_RS26965 (OG842_26955) vraR 6000009..6000692 (-) 684 WP_266733249.1 response regulator transcription factor Regulator
  OG842_RS26970 (OG842_26960) - 6000689..6002035 (-) 1347 WP_266733251.1 sensor histidine kinase -
  OG842_RS26975 (OG842_26965) - 6002152..6003120 (-) 969 WP_266733253.1 DUF4429 domain-containing protein -
  OG842_RS26980 (OG842_26970) - 6003205..6004416 (-) 1212 WP_266733255.1 alpha/beta hydrolase -
  OG842_RS26985 (OG842_26975) - 6004662..6005327 (-) 666 WP_266733257.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24196.00 Da        Isoelectric Point: 5.1230

>NTDB_id=650267 OG842_RS26965 WP_266733249.1 6000009..6000692(-) (vraR) [Streptomyces sp. NBC_00376]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGRRAIDVSRSVRPDVVLMDVRMPEMDGLAAARELLDPPVGVVHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGEALLAPSVTRRLIADFARQGPTGATRSGQSLRLN
GLTPRETEVLELIARGLSNQEIAGKLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYEAGVVVPGEG

Nucleotide


Download         Length: 684 bp        

>NTDB_id=650267 OG842_RS26965 WP_266733249.1 6000009..6000692(-) (vraR) [Streptomyces sp. NBC_00376]
TTGACCATTCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGGTTCGCGGCACTGCTCGCGGCGCAGAGCGA
CATCGACGTGGTCGGTGAGGCGCCGGACGGACGCCGGGCCATCGACGTCAGCCGCAGCGTCCGCCCGGACGTGGTCCTGA
TGGATGTCCGGATGCCCGAGATGGACGGCCTGGCGGCGGCCCGCGAGCTGCTGGACCCGCCGGTGGGGGTGGTGCACCGG
CCGAAGGTGCTGATGCTCACCACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCGTCCGGCTTCCT
GCTGAAGGACGCGCCGCCCGCCGATCTGATCTCGGCGGTACGGGTGGTCGCGGCGGGCGAGGCGCTGCTCGCGCCGTCCG
TGACGCGCCGCCTGATCGCGGACTTCGCCCGGCAGGGCCCGACCGGGGCCACCCGGAGCGGCCAGTCGCTGCGGCTGAAC
GGCCTGACTCCGCGCGAGACGGAGGTACTCGAACTGATCGCGCGGGGCCTGTCGAACCAGGAGATCGCGGGGAAGCTGGT
GCTGGCCGAGCAGACGGTGAAGACCCACATAGGCCGGGTGCTGGCCAAGCTGGACCTGCGGGACCGGGCACAGGCGGTGA
TCTTCGCGTACGAGGCGGGGGTCGTGGTGCCGGGCGAGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.359

98.238

0.396
  degU Bacillus subtilis subsp. subtilis str. 168

37.004

100

0.37