Detailed information NTG0650117

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: L2Z22_RS12670
• Genome accession: NZ_CP091353
• Coordinates: 2579802..2582234 (-)
• Length: 810 a.a.
• NCBI ID: WP_000472705.1
• Uniprot ID: A0A231SZ39
• Organism: Acinetobacter baumannii strain AB189-VUB
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	2575125..2587264	2579802..2582234	within	0

Gene organization within MGE regions

Location: 2575125..2587264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L2Z22_RS12645 (L2Z22_12640)	purM	2575125..2576195 (+)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-
L2Z22_RS12650 (L2Z22_12645)	purN	2576192..2576821 (+)	630	WP_000975536.1	phosphoribosylglycinamide formyltransferase	-
L2Z22_RS12655 (L2Z22_12650)	-	2576885..2577694 (-)	810	WP_000114076.1	alpha/beta hydrolase	-
L2Z22_RS12660 (L2Z22_12655)	sppA	2577713..2578729 (-)	1017	WP_001286615.1	signal peptide peptidase SppA	-
L2Z22_RS12665 (L2Z22_12660)	-	2578866..2579849 (+)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
L2Z22_RS12670 (L2Z22_12665)	comA/comEC	2579802..2582234 (-)	2433	WP_000472705.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
L2Z22_RS12675 (L2Z22_12670)	lolD	2582320..2583006 (-)	687	WP_000049403.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
L2Z22_RS12680 (L2Z22_12675)	-	2582999..2584234 (-)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
L2Z22_RS12685 (L2Z22_12680)	-	2584482..2585390 (-)	909	WP_001140078.1	EamA family transporter	-
L2Z22_RS12690 (L2Z22_12685)	-	2585401..2585886 (-)	486	WP_001985538.1	YaiI/YqxD family protein	-
L2Z22_RS12695 (L2Z22_12690)	-	2586143..2587084 (+)	942	WP_000795874.1	hypothetical protein	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92426.69 Da
• Isoelectric Point: 8.6357

>NTDB_id=650117 L2Z22_RS12670 WP_000472705.1 2579802..2582234(-) (comA/comEC) [Acinetobacter baumannii strain AB189-VUB]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNFSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSAFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQQFL
SLSSKMIFMGKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFIVKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISFAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=650117 L2Z22_RS12670 WP_000472705.1 2579802..2582234(-) (comA/comEC) [Acinetobacter baumannii strain AB189-VUB]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGACCAATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATTTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAATGGTTTATTCAGCGAAATATTATGTCTGGTTTTAATGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGCATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACAGTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGGGTAAGGTGTTAATTGAGTCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTATAGTAAAACCGTTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTTTGCCATAATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAACAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAA
GCCATTTTTTTACAACATTCCGAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCAGGATGGGAAGCCGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAATCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-639)

• Competence protein (Competence) (243-521)

3D structure

• AlphaFold DB: A0A231SZ39

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.025	100	0.98
comA/comEC	Acinetobacter baumannii strain A118	97.037	100	0.97
comA/comEC	Acinetobacter baylyi ADP1	50.246	100	0.504