Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG959_RS20215 Genome accession   NZ_CP107951
Coordinates   4528285..4528962 (+) Length   225 a.a.
NCBI ID   WP_148019907.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00385     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4523285..4533962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG959_RS20195 (OG959_20210) kynU 4523937..4525142 (+) 1206 WP_326660368.1 kynureninase -
  OG959_RS20200 (OG959_20215) - 4525256..4525870 (+) 615 WP_326660370.1 SUKH-4 family immunity protein -
  OG959_RS20205 (OG959_20220) - 4525988..4526863 (+) 876 WP_326660372.1 alpha/beta hydrolase -
  OG959_RS20210 (OG959_20225) - 4526975..4528288 (+) 1314 WP_326660374.1 histidine kinase -
  OG959_RS20215 (OG959_20230) vraR 4528285..4528962 (+) 678 WP_148019907.1 response regulator transcription factor Regulator
  OG959_RS20220 (OG959_20235) - 4529044..4530279 (+) 1236 WP_326660376.1 cytochrome P450 -
  OG959_RS20225 (OG959_20240) - 4530354..4531982 (-) 1629 WP_326660378.1 ABC transporter permease -
  OG959_RS20230 (OG959_20245) - 4531979..4532917 (-) 939 WP_326660379.1 ABC transporter ATP-binding protein -
  OG959_RS20235 (OG959_20250) - 4533021..4533575 (+) 555 WP_326660380.1 MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23951.78 Da        Isoelectric Point: 4.8026

>NTDB_id=650094 OG959_RS20215 WP_148019907.1 4528285..4528962(+) (vraR) [Streptomyces sp. NBC_00385]
MTAAAGTPIRVLIVDDQMMVREGFSVLLNAMPGIEVVGEAVNGREAVAQVAALRPDVVLMDIRMPELNGIEATREIVAAD
ADAKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTRRLITEFSKLAAAPRPPALAQIG
DLTERETEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=650094 OG959_RS20215 WP_148019907.1 4528285..4528962(+) (vraR) [Streptomyces sp. NBC_00385]
ATGACGGCCGCCGCCGGTACGCCGATCCGGGTGCTCATCGTCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCT
GCTCAACGCGATGCCGGGCATCGAGGTCGTCGGCGAGGCCGTCAACGGGCGGGAGGCCGTCGCCCAGGTCGCGGCGCTCC
GTCCCGACGTGGTGCTGATGGACATCCGGATGCCGGAGCTCAACGGCATCGAGGCGACCCGCGAGATCGTCGCCGCCGAC
GCGGACGCGAAGGTGCTGGTGCTCACCACCTTCGATCTCGACGAGTACGTCTACCAGGCGCTGCGTGCCGGTGCGTCCGG
CTTCCTCCTCAAGGACGCCTCGGCCCGGCAACTCGCGGACGGTGTACGTGTGGTGGCGTCCGGCGAGGCGCTTCTCGCCC
CCACGGTCACCCGTCGTCTGATCACCGAGTTCTCCAAGCTCGCGGCGGCCCCGCGGCCGCCGGCCCTGGCCCAGATCGGC
GACCTCACGGAGCGCGAGACGGAAGTGCTCGTCCTGATCGCCCAGGGCCTGTCGAATGCGGAGATCGCCTCGCATCTGGT
GGTCGCCGAGTCCACCATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGCCTGCGCGACCGCACCCAGGCGGCCG
TCTTCGCCTACGAGGCCCGGCTGGTCACGCCGTCGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-120)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.86

95.111

0.427
  degU Bacillus subtilis subsp. subtilis str. 168

42.922

97.333

0.418