Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG959_RS07625 Genome accession   NZ_CP107951
Coordinates   1751418..1752095 (-) Length   225 a.a.
NCBI ID   WP_326657423.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00385     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1746418..1757095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG959_RS07600 (OG959_07615) - 1747630..1748313 (+) 684 WP_326657418.1 response regulator -
  OG959_RS07605 (OG959_07620) - 1748330..1748728 (-) 399 WP_326657419.1 helix-turn-helix domain-containing protein -
  OG959_RS07610 (OG959_07625) - 1748834..1749196 (+) 363 WP_326657420.1 DoxX family protein -
  OG959_RS07615 (OG959_07630) - 1749254..1750846 (-) 1593 WP_326657422.1 cation acetate symporter -
  OG959_RS07620 (OG959_07635) - 1750843..1751286 (-) 444 WP_326666266.1 DUF485 domain-containing protein -
  OG959_RS07625 (OG959_07640) vraR 1751418..1752095 (-) 678 WP_326657423.1 response regulator transcription factor Regulator
  OG959_RS07630 (OG959_07645) - 1752092..1753258 (-) 1167 WP_326657424.1 histidine kinase -
  OG959_RS07635 (OG959_07650) - 1753255..1753773 (-) 519 WP_326657425.1 DUF1453 domain-containing protein -
  OG959_RS07640 (OG959_07655) - 1753932..1756052 (-) 2121 WP_326657426.1 DNA topoisomerase IV subunit B -
  OG959_RS07645 (OG959_07660) - 1756487..1756720 (+) 234 WP_024489001.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23990.45 Da        Isoelectric Point: 4.7225

>NTDB_id=650062 OG959_RS07625 WP_326657423.1 1751418..1752095(-) (vraR) [Streptomyces sp. NBC_00385]
MTARVVVADDQSVVREGIVMLLGLLPGIEVVGSAKDGEEAVALVAEHAPDVVLMDLRMPRCDGVEATRRIRTEFPGTQVV
VLTTFDDDDSLFPALRAGARGYLTKDAGGDEIVRAVQAVLSGEAGLSPAIQRRLLEQVTEGPLPRAVSDVPELPDGMTPR
EAEVLVLIADGMSNAEIARSLHISQATVKSHINNLFAKAGLRDRAQAVRYAYVRGIAQPPGTTFT

Nucleotide


Download         Length: 678 bp        

>NTDB_id=650062 OG959_RS07625 WP_326657423.1 1751418..1752095(-) (vraR) [Streptomyces sp. NBC_00385]
GTGACCGCGCGGGTAGTGGTCGCCGACGATCAGTCGGTGGTGCGTGAGGGGATCGTCATGCTGCTGGGGCTGCTGCCCGG
GATCGAGGTGGTCGGTTCGGCGAAGGACGGGGAGGAGGCCGTCGCTCTTGTGGCCGAGCACGCCCCGGACGTTGTCCTGA
TGGACCTGCGGATGCCCCGCTGCGACGGGGTGGAGGCGACGCGCCGCATCCGCACGGAATTCCCCGGCACACAGGTCGTG
GTGCTGACGACCTTCGACGACGACGACTCGCTCTTCCCGGCGCTCCGGGCGGGAGCTCGCGGGTACCTGACGAAGGACGC
GGGGGGTGACGAGATCGTGCGGGCCGTCCAGGCCGTGCTCTCCGGAGAGGCGGGGCTCTCGCCCGCCATTCAGCGCCGTC
TGCTGGAACAGGTCACCGAGGGGCCACTTCCGCGGGCGGTGAGCGATGTGCCGGAGCTGCCTGACGGGATGACTCCCCGT
GAGGCCGAGGTGCTGGTTCTGATCGCCGACGGGATGTCCAACGCGGAGATCGCCCGGAGCCTCCACATTTCGCAGGCCAC
CGTGAAGAGCCACATCAACAACCTGTTCGCCAAGGCCGGGCTCCGCGACCGGGCCCAGGCGGTCCGCTATGCGTACGTTC
GAGGGATCGCACAGCCGCCCGGGACAACCTTCACCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.45

96.889

0.382
  degU Bacillus subtilis subsp. subtilis str. 168

36.771

99.111

0.364