Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG780_RS41935 Genome accession   NZ_CP107950
Coordinates   9585440..9586132 (+) Length   230 a.a.
NCBI ID   WP_328457341.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00386     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9580440..9591132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG780_RS41910 (OG780_41900) - 9580687..9581580 (-) 894 WP_328457331.1 aldo/keto reductase -
  OG780_RS41915 (OG780_41905) - 9581577..9582134 (-) 558 WP_328457333.1 TetR family transcriptional regulator -
  OG780_RS41920 (OG780_41910) - 9582452..9582868 (+) 417 WP_328457335.1 hypothetical protein -
  OG780_RS41925 (OG780_41915) - 9583299..9584177 (+) 879 WP_328457337.1 CPBP family intramembrane glutamic endopeptidase -
  OG780_RS41930 (OG780_41920) - 9584206..9585435 (+) 1230 WP_328457339.1 histidine kinase -
  OG780_RS41935 (OG780_41925) vraR 9585440..9586132 (+) 693 WP_328457341.1 response regulator transcription factor Regulator
  OG780_RS41940 (OG780_41930) - 9586643..9587887 (-) 1245 WP_328457343.1 WD40 repeat domain-containing protein -
  OG780_RS41945 (OG780_41935) - 9588060..9588683 (-) 624 WP_328457345.1 hypothetical protein -
  OG780_RS41950 (OG780_41940) - 9588989..9590383 (-) 1395 WP_328457347.1 hypothetical protein -
  OG780_RS41955 (OG780_41945) - 9590429..9591088 (+) 660 Protein_8290 DUF4291 family protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24971.78 Da        Isoelectric Point: 5.3612

>NTDB_id=650046 OG780_RS41935 WP_328457341.1 9585440..9586132(+) (vraR) [Streptomyces sp. NBC_00386]
MSDAPQPIRVLVCDDQELVRTGYVTIFSAQPDIEVVGEAENGHAAVEAVRRLRPDVVVMDIRMPLLDGIQATRQLAGPDA
EFPPKVLVVTTFNVDAYVYDALRAGASGFLLKDAPPAELVNGIRTVARGEALLAPAVTRHLIGHFAEHLRPADTSRQARE
DLVRALTPRELDVLRQIAEGLSNAEIATALFITPETVKTYVSRILAKLGLRDRVQAVVLAYRVGLIPAAD

Nucleotide


Download         Length: 693 bp        

>NTDB_id=650046 OG780_RS41935 WP_328457341.1 9585440..9586132(+) (vraR) [Streptomyces sp. NBC_00386]
GTGAGCGATGCGCCGCAACCCATCCGTGTACTCGTCTGCGACGACCAGGAACTGGTGCGGACCGGCTACGTCACCATCTT
CTCCGCGCAGCCCGACATCGAGGTCGTCGGGGAGGCCGAGAACGGGCACGCGGCGGTGGAAGCCGTACGGCGGCTGCGGC
CCGACGTGGTGGTGATGGACATCCGGATGCCCCTGCTCGACGGCATCCAGGCGACCCGGCAACTGGCCGGTCCCGATGCC
GAGTTCCCGCCGAAGGTGCTGGTCGTCACCACGTTCAACGTCGATGCCTATGTCTACGACGCGCTGCGGGCCGGAGCCAG
CGGCTTCCTCCTCAAGGACGCGCCTCCCGCGGAGCTGGTGAACGGGATCCGTACGGTCGCCCGGGGCGAGGCCCTGCTGG
CGCCCGCCGTCACCCGCCACCTCATAGGTCACTTCGCCGAACACCTGCGGCCGGCCGACACCTCCAGGCAGGCCAGGGAA
GACCTCGTACGCGCGCTGACCCCCCGCGAGCTCGACGTGCTCCGGCAGATCGCCGAGGGGCTGTCGAACGCGGAGATCGC
CACGGCACTGTTCATCACCCCCGAGACGGTCAAGACCTACGTTTCGCGGATCCTGGCCAAACTCGGCCTGCGCGACCGGG
TCCAGGCGGTCGTCCTCGCCTACCGGGTCGGGCTGATCCCAGCGGCCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(10-123)

Bacterial regulatory proteins, luxR family (GerE)

(165-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.271

96.087

0.387
  degU Bacillus subtilis subsp. subtilis str. 168

36.842

99.13

0.365