Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG917_RS18645 Genome accession   NZ_CP107948
Coordinates   4139616..4140284 (+) Length   222 a.a.
NCBI ID   WP_328318740.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00388     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4134616..4145284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG917_RS18620 (OG917_18640) - 4135100..4135927 (+) 828 WP_328318737.1 tryptophan 2,3-dioxygenase family protein -
  OG917_RS18625 (OG917_18645) - 4135920..4136069 (+) 150 WP_328318738.1 hypothetical protein -
  OG917_RS18630 (OG917_18650) kynU 4136102..4137259 (+) 1158 WP_328322001.1 kynureninase -
  OG917_RS18635 (OG917_18655) - 4137315..4138166 (+) 852 WP_328318739.1 alpha/beta hydrolase -
  OG917_RS18640 (OG917_18660) - 4138351..4139619 (+) 1269 WP_328322003.1 histidine kinase -
  OG917_RS18645 (OG917_18665) vraR 4139616..4140284 (+) 669 WP_328318740.1 response regulator transcription factor Regulator
  OG917_RS18650 (OG917_18670) - 4140306..4141949 (-) 1644 WP_328318741.1 ABC transporter permease -
  OG917_RS18655 (OG917_18675) - 4141946..4142902 (-) 957 WP_328318742.1 ABC transporter ATP-binding protein -
  OG917_RS18660 (OG917_18680) - 4143004..4143525 (+) 522 WP_328318743.1 MarR family transcriptional regulator -
  OG917_RS18665 (OG917_18685) - 4143554..4144405 (-) 852 WP_328318744.1 diacylglycerol kinase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23856.63 Da        Isoelectric Point: 4.7297

>NTDB_id=649935 OG917_RS18645 WP_328318740.1 4139616..4140284(+) (vraR) [Streptomyces sp. NBC_00388]
MSAPAIRVLVVDDQMMVREGFSVLLNAMPDIEVVGEAVNGVEAVAQVAALRPDVVLMDIRMPELNGIEATRAIVAADESA
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLAEGVRVVASGEALLAPTITKRLIVEFSRLSDAPRQPSLARVDELT
ERESEVLVLIAHGLSNAEIASRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYETGLVRPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=649935 OG917_RS18645 WP_328318740.1 4139616..4140284(+) (vraR) [Streptomyces sp. NBC_00388]
ATGAGCGCCCCGGCCATCAGGGTCCTTGTCGTCGACGACCAGATGATGGTCCGCGAGGGATTCTCGGTCCTGCTCAACGC
GATGCCGGACATCGAGGTCGTGGGCGAGGCGGTCAACGGTGTCGAGGCGGTGGCCCAGGTGGCCGCCCTGCGCCCGGACG
TCGTCCTGATGGACATCCGGATGCCCGAACTGAACGGCATAGAGGCGACCCGCGCGATCGTCGCGGCGGACGAGTCGGCG
AAGGTACTGGTCCTGACCACCTTCGACCTGGACGAGTACGTCTACCAGGCGCTGCGCGCCGGGGCTTCGGGCTTCCTGCT
GAAGGACGCGTCCGCCCGCCAGCTGGCCGAGGGCGTACGCGTGGTGGCGTCAGGGGAGGCCCTGCTCGCTCCCACCATCA
CCAAGCGGCTGATCGTCGAGTTCTCCCGGCTGTCGGACGCGCCCAGGCAGCCCTCGCTCGCCAGGGTCGACGAGCTCACG
GAGCGCGAGAGCGAGGTGCTCGTCCTGATCGCGCACGGCCTGTCGAACGCGGAGATCGCCTCCCGGCTGGTCGTCGCCGA
GTCGACGATCAAGACGCATGTGAGCCGGATCCTGGTGAAGCTCGGCCTGCGCGACCGGACCCAGGCGGCGGTCTTCGCGT
ACGAGACGGGTCTGGTCAGGCCGGGGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-118)

Bacterial regulatory proteins, luxR family (GerE)

(158-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.779

97.748

0.428
  degU Bacillus subtilis subsp. subtilis str. 168

42.601

100

0.428