Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS70_RS32690 Genome accession   NZ_CP107945
Coordinates   7361277..7361942 (+) Length   221 a.a.
NCBI ID   WP_328403464.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00390     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7356277..7366942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS70_RS32665 (OHS70_32725) - 7356412..7357692 (+) 1281 WP_328403453.1 geranylgeranyl reductase family protein -
  OHS70_RS32670 (OHS70_32730) - 7358009..7358314 (+) 306 WP_328403455.1 hypothetical protein -
  OHS70_RS32675 (OHS70_32735) - 7358487..7358936 (-) 450 WP_328403458.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHS70_RS32680 (OHS70_32740) - 7359079..7359819 (+) 741 WP_328403460.1 TetR/AcrR family transcriptional regulator -
  OHS70_RS32685 (OHS70_32745) - 7360054..7361280 (+) 1227 WP_328403462.1 sensor histidine kinase -
  OHS70_RS32690 (OHS70_32750) vraR 7361277..7361942 (+) 666 WP_328403464.1 response regulator transcription factor Regulator
  OHS70_RS32695 (OHS70_32755) - 7361903..7362178 (-) 276 WP_328403466.1 DUF6332 family protein -
  OHS70_RS32700 (OHS70_32760) - 7362435..7362833 (-) 399 WP_328403468.1 hypothetical protein -
  OHS70_RS32705 (OHS70_32765) - 7362856..7363284 (-) 429 WP_328403470.1 protease inhibitor I42 family protein -
  OHS70_RS32710 (OHS70_32770) - 7363293..7364870 (-) 1578 WP_328403472.1 peptidoglycan-binding protein -
  OHS70_RS32715 (OHS70_32775) - 7364885..7365268 (-) 384 WP_328403474.1 hypothetical protein -
  OHS70_RS32720 (OHS70_32780) - 7365343..7365978 (-) 636 WP_328403476.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24183.93 Da        Isoelectric Point: 4.7458

>NTDB_id=649897 OHS70_RS32690 WP_328403464.1 7361277..7361942(+) (vraR) [Streptomyces sp. NBC_00390]
MIRVLLADDQMLVRAGFRALLDAQHDIEVAGEACDGEEAVRLTGELRPDVVLMDIRMPVLDGLAATRRITGDERLHEVKV
VMLTTFEIDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVEGDALLSPGVTRRLIAEFAARSKAPADAEGLSELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=649897 OHS70_RS32690 WP_328403464.1 7361277..7361942(+) (vraR) [Streptomyces sp. NBC_00390]
GTGATCCGCGTACTGCTCGCCGACGACCAGATGCTGGTCCGGGCAGGCTTCCGGGCCCTGCTCGACGCCCAGCACGACAT
CGAGGTGGCGGGCGAGGCCTGCGACGGCGAGGAGGCGGTGCGCCTGACCGGTGAACTGCGCCCGGACGTGGTCCTGATGG
ACATCCGGATGCCGGTCCTCGACGGCTTGGCCGCCACCCGCCGGATCACCGGGGACGAGCGGCTGCACGAGGTCAAGGTG
GTCATGCTCACCACCTTCGAAATCGACGAGTACGTCTTCGAGGCCATCCGCTCGGGCGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCGGAGGAACTGCTGCGCGCCGTACGGGCGGTGGTGGAGGGGGACGCGCTGCTCTCGCCGGGCGTCACGCGCC
GCCTCATCGCCGAGTTCGCGGCCCGCTCGAAGGCGCCGGCCGATGCCGAGGGCCTGAGTGAACTCACCGAACGGGAACGC
GAGGTGATGGCACTGGTCGGCATCGGCCTGTCCAACGAGGAGATCGCCCGCCGGCTTGTGGTCAGCCCGCTCACGGCGAA
GACGCATGTGAGCCGCACGATGGTGAAGCTGGGTGCGCGCGACCGAGCCCAACTCGTCGTACTCGCCTATGAGTCGGGGC
TGGTGCGGCCCGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.285

0.371
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.367